Pub. Date : 2011 Nov
PMID : 21224019
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Synthesis of d-serine is carried out by serine racemase (SR), a pyridoxal 5"-phosphate-dependent enzyme. | D-serine | serine racemase | Homo sapiens |
2 | Synthesis of d-serine is carried out by serine racemase (SR), a pyridoxal 5"-phosphate-dependent enzyme. | D-serine | serine racemase | Homo sapiens |
3 | I propose a role for SR in a novel form of astrocyte-neuron communication-the "serine shuttle", whereby astrocytes synthesize and export l-serine required for the synthesis of d-serine by the predominantly neuronal SR. | D-serine | serine racemase | Homo sapiens |
4 | The higher content of d-serine in astrocytes appears to be related to increased d-serine stability, for their low SR expression will prevent substantial d-serine metabolism via alpha,beta-elimination. | D-serine | serine racemase | Homo sapiens |