Tunicamycin

eukaryotic translation initiation factor 2 alpha kinase 3 ; Homo sapiens







34 Article(s)
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1 35233582 The role of GRP78 in oxidative stress induced by tunicamycin in trabecular meshwork cells. 2022 Mar 2 1
2 32979141 Naringin Combined with NF-κB Inhibition and Endoplasmic Reticulum Stress Induces Apoptotic Cell Death via Oxidative Stress and the PERK/eIF2α/ATF4/CHOP Axis in HT29 Colon Cancer Cells. 2021 Feb 1
3 33846370 The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells. 2021 Apr 12 1
4 34143952 Bi-allelic variants in the ER quality-control mannosidase gene EDEM3 cause a congenital disorder of glycosylation. 2021 Jul 1 2
5 34533242 Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway. 2021 Nov 1
6 34716302 Reciprocal regulation between ER stress and autophagy in renal tubular fibrosis and apoptosis. 2021 Oct 29 2
7 34725321 PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells. 2021 Nov 1 1
8 31974624 ΜicroRNA‑421 participates in vitiligo development through regulating human melanocyte survival by targeting receptor‑interacting serine/threonine kinase 1. 2020 Feb 4
9 32035621 The unc-51 like autophagy activating kinase 1-autophagy related 13 complex has distinct functions in tunicamycin-treated cells. 2020 Apr 9 1
10 32040528 1,25-hydroxyvitamin D3 decreases endoplasmic reticulum stress-induced inflammatory response in mammary epithelial cells. 2020 4
11 32660483 In vitro treatment of 3 T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin sensitivity through inhibition of autophagy via the mTOR/CREB signaling pathway. 2020 Jul 13 1
12 33014334 Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma. 2020 1
13 30770792 Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress. 2019 Feb 15 2
14 30926605 The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress. 2019 May 17 1
15 31534165 ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation. 2019 Sep 18 1
16 31861550 Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin. 2019 Dec 19 1
17 29620275 Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway. 2018 Jun 1
18 28460451 Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation. 2017 Apr 18 2
19 28522733 Activation of PERK Elicits Memory Impairment through Inactivation of CREB and Downregulation of PSD95 After Traumatic Brain Injury. 2017 Jun 14 1
20 28630443 Chemical chaperone, TUDCA unlike PBA, mitigates protein aggregation efficiently and resists ER and non-ER stress induced HepG2 cell death. 2017 Jun 19 1
21 28631572 Endoplasmic reticulum stress could induce autophagy and apoptosis and enhance chemotherapy sensitivity in human esophageal cancer EC9706 cells by mediating PI3K/Akt/mTOR signaling pathway. 2017 Jun 1
22 28720827 Small chaperons and autophagy protected neurons from necrotic cell death. 2017 Jul 18 1
23 26472337 Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress. 2016 Feb 2
24 26718307 PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage. 2016 Mar 1
25 27322083 Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis. 2016 Aug 9 2
26 27330716 Endoplasmic reticulum stress induced by tunicamycin increases resistin messenger ribonucleic acid through the pancreatic endoplasmic reticulum eukaryotic initiation factor 2α kinase-activating transcription factor 4-CAAT/enhancer binding protein-α homologous protein pathway in THP-1 human monocytes. 2016 May 2
27 25428129 mTOR contributes to ER stress and associated apoptosis in renal tubular cells. 2015 Feb 1 2
28 25737469 An ATF4-Signal-Modulating Machine Other Than GADD34 Acts in ATF4-to-CHOP Signaling to Block CHOP Expression in ER-Stress-Related Autophagy. 2015 Jul 1
29 22550476 Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes. 2012 1
30 21640381 Carbon monoxide, a reaction product of heme oxygenase-1, suppresses the expression of C-reactive protein by endoplasmic reticulum stress through modulation of the unfolded protein response. 2011 Sep 1
31 17624530 IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells. 2008 May 1
32 18544642 Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines. 2008 Aug 1
33 17525289 Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells. 2007 Oct 1 1
34 15572843 [Protective effects of HRD1 and 4-phenylbutyric acid against neuronal cell death]. 2004 Dec 1