Benzo(a)pyrene

aryl-hydrocarbon receptor ; Mus musculus







81 Article(s)
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1 34890772 The behavioral effects of gestational and lactational benzo[a]pyrene exposure vary by sex and genotype in mice with differences at the Ahr and Cyp1a2 loci. 2022 Jan-Feb 2
2 34998820 Oral benzo[a]pyrene administration attenuates dextran sulfate sodium-induced colitis in mice. 2022 Feb 1 3
3 35057794 Molecular mechanism of benzo [a] pyrene regulating lipid metabolism via aryl hydrocarbon receptor. 2022 Jan 20 9
4 35065163 Therapeutic role of eicosapentaenoic and arachidonic acid in benzo(a) pyrene-induced toxicity in HUVEC endothelial cells. 2022 Mar 15 1
5 35203386 Aryl Hydrocarbon Receptor Activation by Benzo[a]pyrene Prevents Development of Septic Shock and Fatal Outcome in a Mouse Model of Systemic Salmonella enterica Infection. 2022 Feb 20 3
6 35567930 Benzo[a]pyrene exposure in muscle triggers sarcopenia through aryl hydrocarbon receptor-mediated reactive oxygen species production. 2022 May 11 1
7 33977171 Benzo[a]pyrene Cytotoxicity Tolerance in Testicular Sertoli Cells Involves Aryl-hydrocarbon Receptor and Cytochrome P450 1A1 Expression Deficiencies. 2021 Mar 1
8 34290363 Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis. 2021 Jul 21 1
9 31811747 Therapeutic potential of aryl hydrocarbon receptor ligands derived from natural products in rheumatoid arthritis. 2020 Jun 1
10 32062438 Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression. 2020 Apr 2
11 32417428 Comparative toxicity analysis of corannulene and benzo[a]pyrene in mice. 2020 Oct 1 1
12 32557721 Activation of aryl hydrocarbon receptor by benzo[a]pyrene increases interleukin 33 expression and eosinophil infiltration in a mouse model of allergic airway inflammation. 2020 Nov 6
13 32684523 Benzo[a]pyrene injures BMP2-induced osteogenic differentiation of mesenchymal stem cells through AhR reducing BMPRII. 2020 Oct 15 3
14 32808713 6-Formylindolo[3,2-b]carbazole reduces apoptosis induced by benzo[a]pyrene in a mitochondrial-dependent manner. 2020 Dec 4
15 33324084 Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice. 2020 1
16 30748024 Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T-helper 2-driven proinflammatory responses in a mouse model of allergic dermatitis. 2019 Jul 1
17 30982974 Benzo(a)pyrene facilitates dermatophagoides group 1 (Der f 1)-induced epithelial cytokine release through aryl hydrocarbon receptor in asthma. 2019 Sep 6
18 31086989 A CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1. 2019 Aug 1 2
19 31660294 Antitumor activity of Cuphea ignea extract against benzo(a)pyrene-induced lung tumorigenesis in Swiss Albino mice. 2019 1
20 30053493 Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner. 2018 Nov 1 3
21 30099064 Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. 2018 Oct 15 6
22 30165701 Cigarette Smoke Toxins-Induced Mitochondrial Dysfunction and Pancreatitis Involves Aryl Hydrocarbon Receptor Mediated Cyp1 Gene Expression: Protective Effects of Resveratrol. 2018 Dec 1 2
23 28007926 Circadian Regulation of Benzo[a]Pyrene Metabolism and DNA Adduct Formation in Breast Cells and the Mouse Mammary Gland. 2017 Mar 1
24 27293999 The aryl hydrocarbon receptor agonist benzo(a)pyrene reactivates LINE-1 in HepG2 cells through canonical TGF-β1 signaling: implications in hepatocellular carcinogenesis. 2016 1
25 27849171 The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis. 2016 Dec 15 1
26 28116098 Cyp1b1-mediated suppression of lymphoid progenitors in bone marrow by polycyclic aromatic hydrocarbons coordinately impacts spleen and thymus: a selective role for the Ah Receptor. 2016 Aug 1
27 26215100 Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR). 2015 Oct 2 3
28 25178717 Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation. 2014 Nov 1 1
29 25233930 Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway. 2014 Nov 2
30 23776235 Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. 2013 Jul 2 4
31 23800876 The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2013 Sep 1 1
32 21567390 Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene. 2012 Mar 4
33 22228805 Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. 2012 Apr 8
34 22486318 Regulation of the activity and expression of aryl hydrocarbon receptor by ethanol in mouse hepatic stellate cells. 2012 Nov 2
35 22561122 FICZ, a tryptophan photoproduct, suppresses pulmonary eosinophilia and Th2-type cytokine production in a mouse model of ovalbumin-induced allergic asthma. 2012 Aug 2
36 21177068 Role of sulforaphane in the anti-initiating mechanism of lung carcinogenesis in vivo by modulating the metabolic activation and detoxification of benzo(a)pyrene. 2011 Feb 2
37 21252291 Acute disruption of bone marrow hematopoiesis by benzo(a)pyrene is selectively reversed by aryl hydrocarbon receptor-mediated processes. 2011 Apr 2
38 21569818 Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage. 2011 Jul 29 2
39 21569840 Nrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalase. 2011 Jul 1 2
40 21803694 A mutant Ahr allele protects the embryonic kidney from hydrocarbon-induced deficits in fetal programming. 2011 Dec 2
41 20478378 Overexpression of antioxidant enzymes upregulates aryl hydrocarbon receptor expression via increased Sp1 DNA-binding activity. 2010 Aug 1 2
42 20570689 Flavin-containing monooxygenase-3: induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver. 2010 Aug 15 1
43 19216581 Biotransformation of benzo[a]pyrene in Ahr knockout mice is dependent on time and route of exposure. 2009 Mar 16 10
44 19351592 Inhibition of ischemia-induced angiogenesis by benzo[a]pyrene in a manner dependent on the aryl hydrocarbon receptor. 2009 Mar 27 5
45 19666105 Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells. 2009 Oct 15 3
46 19755658 The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene. 2009 Nov 4
47 18096572 Analysis of Ah receptor-ARNT and Ah receptor-ARNT2 complexes in vitro and in cell culture. 2008 May 2
48 18179178 Characterization of the antiallergic drugs 3-[2-(2-phenylethyl) benzoimidazole-4-yl]-3-hydroxypropanoic acid and ethyl 3-hydroxy-3-[2-(2-phenylethyl)benzoimidazol-4-yl]propanoate as full aryl hydrocarbon receptor agonists. 2008 Feb 2
49 18664595 Suppression of adipocyte differentiation by Cordyceps militaris through activation of the aryl hydrocarbon receptor. 2008 Oct 1
50 17275222 Benzo(a)pyrene inhibits growth and functional differentiation of mouse bone marrow-derived dendritic cells. Downregulation of RelB and eIF3 p170 by benzo(a)pyrene. 2007 Feb 28 4