Pub. Date : 2018 Oct 15
PMID : 30099064
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aryl hydrocarbon receptor activation by benzo(a)pyrene inhibits proliferation of myeloid precursor cells and alters the differentiation state as well as the functional phenotype of murine bone marrow-derived macrophages. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |
| 2 | Our results show that the activation of AhR by subtoxic doses of the AhR ligand benzo(a)pyrene (BaP) impaired the proliferation of bone marrow cells (BMCs) whereas the proportion of resulting adherent cells was not affected. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |
| 3 | Our results show that the activation of AhR by subtoxic doses of the AhR ligand benzo(a)pyrene (BaP) impaired the proliferation of bone marrow cells (BMCs) whereas the proportion of resulting adherent cells was not affected. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |
| 4 | Our results show that the activation of AhR by subtoxic doses of the AhR ligand benzo(a)pyrene (BaP) impaired the proliferation of bone marrow cells (BMCs) whereas the proportion of resulting adherent cells was not affected. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |
| 5 | Our results show that the activation of AhR by subtoxic doses of the AhR ligand benzo(a)pyrene (BaP) impaired the proliferation of bone marrow cells (BMCs) whereas the proportion of resulting adherent cells was not affected. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |
| 6 | However, expression of the murine macrophage marker F4/80, the major histocompatibility complex class II (MHC-II) and the Fcgamma receptor I (FcgammaRI/CD64) were upregulated on BaP-exposed BMMs in an AhR-dependent manner. | Benzo(a)pyrene | aryl-hydrocarbon receptor | Mus musculus |