Title : Nrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalase.

Pub. Date : 2011 Jul 1

PMID : 21569840






2 Functional Relationships(s)
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1 Knockdown of AhR by RNA interference diminished BaP-induced expression of Nrf2 and NQO1. Benzo(a)pyrene aryl-hydrocarbon receptor Mus musculus
2 These results suggest that catalase overexpression upregulates BaP-induced NQO1 expression by enhancing the Sp1-AhR-Nrf2 signaling cascade. Benzo(a)pyrene aryl-hydrocarbon receptor Mus musculus