Alcohols

toll-like receptor 4 ; Mus musculus







55 Article(s)
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1 35023943 CD73 Attenuates Alcohol-Induced Liver Injury and Inflammation via Blocking TLR4/MyD88/NF-κB Signaling Pathway. 2022 1
2 35508957 Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through TLR4. 2022 May 4 2
3 34103917 High Mobility Group Box 1/Toll-like Receptor 4 Signaling Increases GABRB3 Expression in Alcohol Exposure. 2021 4
4 34549762 Gut dysbiosis correction contributes to the hepatoprotective effects of Thymus quinquecostatus Celak extract against alcohol through the gut-liver axis. 2021 Oct 19 1
5 34603062 Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice. 2021 4
6 34884634 TLR4 Deficiency Affects the Microbiome and Reduces Intestinal Dysfunctions and Inflammation in Chronic Alcohol-Fed Mice. 2021 Nov 27 1
7 31722525 Rice Bran Phenolic Extract Protects against Alcoholic Liver Injury in Mice by Alleviating Intestinal Microbiota Dysbiosis, Barrier Dysfunction, and Liver Inflammation Mediated by the Endotoxin-TLR4-NF-κB Pathway. 2020 Feb 5 1
8 32050766 Allicin Modifies the Composition and Function of the Gut Microbiota in Alcoholic Hepatic Steatosis Mice. 2020 Mar 11 1
9 30619998 Inhibition of Triggering Receptor Expressed on Myeloid Cells 1 Ameliorates Inflammation and Macrophage and Neutrophil Activation in Alcoholic Liver Disease in Mice. 2019 Jan 1
10 31268779 Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression. 2019 Oct 1 4
11 28864261 The efficacy of (+)-Naltrexone on alcohol preference and seeking behaviour is dependent on light-cycle. 2018 Jan 2
12 28947376 Antagonising TLR4-TRIF signalling before or after a low-dose alcohol binge during adolescence prevents alcohol drinking but not seeking behaviour in adulthood. 2018 Jan 4
13 29156373 Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease. 2018 Apr 1
14 29864452 Binge-like ethanol treatment in adolescence impairs autophagy and hinders synaptic maturation: Role of TLR4. 2018 Aug 24 1
15 29884546 Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease. 2018 Aug 4
16 29932157 Shanxi Aged Vinegar Protects against Alcohol-Induced Liver Injury via Activating Nrf2-Mediated Antioxidant and Inhibiting TLR4-Induced Inflammatory Response. 2018 Jun 22 3
17 30312858 Deletion of TLR-4 attenuates fetal alcohol exposure-induced gene expression and social interaction deficits. 2018 Dec 1
18 30374194 Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex. 2018 Oct 29 1
19 28584078 Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease. 2017 Aug 1
20 28738878 TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders. 2017 Jul 24 2
21 28784931 Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration. 2017 Nov 1
22 29321784 Positive Feedback Regulation between Transglutaminase 2 and Toll-Like Receptor 4 Signaling in Hepatic Stellate Cells Correlates with Liver Fibrosis Post Schistosoma japonicum Infection. 2017 1
23 26858005 Chronic Alcohol Consumption Causes Liver Injury in High-Fructose-Fed Male Mice Through Enhanced Hepatic Inflammatory Response. 2016 Mar 3
24 27151970 Evaluation of TLR4 Inhibitor, T5342126, in Modulation of Ethanol-Drinking Behavior in Alcohol-Dependent Mice. 2016 Sep 1
25 27627966 Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation. 2016 Sep 15 10
26 25427906 Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury. 2015 2
27 25446779 Cytokines and chemokines as biomarkers of ethanol-induced neuroinflammation and anxiety-related behavior: role of TLR4 and TLR2. 2015 Feb 1
28 25542736 Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. 2015 Mar 3
29 25692549 Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease. 2015 2
30 24824124 [TLR4 contributes to intestinal hyperpermeability in alcoholic liver disease]. 2014 Mar 1
31 25003605 The conspiracy of autophagy, stress and inflammation in acute pancreatitis. 2014 Sep 1
32 25175869 Converging actions of alcohol on liver and brain immune signaling. 2014 1
33 25232250 TLR4 signaling and the inhibition of liver hepcidin expression by alcohol. 2014 Sep 14 5
34 25352951 Generation of a mouse model of T-cell lymphoma based on chronic LPS challenge and TGF-β signaling disruption. 2014 Sep 1
35 26201318 Alcohol, TLR4-TGF-β antagonism, and liver cancer. 2014 Sep 3
36 23206318 High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence. 2013 Apr 1 1
37 23500890 Gender differences in alcohol-induced neurotoxicity and brain damage. 2013 Sep 6 2
38 23625200 Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. 2013 Jul 2
39 23951048 Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice. 2013 6
40 23969550 Sex-specific differences in the development of acute alcohol-induced liver steatosis in mice. 2013 Nov-Dec 1
41 21955045 Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. 2012 Mar 7
42 21955082 TLR4-MyD88 signalling: a molecular target for alcohol actions. 2012 Mar 7
43 22782967 Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance. 2012 Sep 3
44 23075869 Innate immunity and alcoholic liver disease. 2012 1
45 21352907 Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage. 2011 Jun 5
46 21463337 A new model of interactive effects of alcohol and high-fat diet on hepatic fibrosis. 2011 Jul 2
47 21463341 Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. 2011 Aug 3
48 20554880 Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage. 2010 Jun 16 1
49 19171902 Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog. 2009 Feb 3 5
50 18061674 Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages. 2008 Apr 1