Polyamines

spermidine/spermine N1-acetyltransferase 1 ; Homo sapiens







172 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34871830 Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine. 2022 Jan 1 1
2 35151773 PEDV infection affects the expression of polyamine-related genes inhibiting viral proliferation. 2022 Apr 15 1
3 33965862 A naphthalimide-polyamine conjugate preferentially accumulates in hepatic carcinoma metastases as a lysosome-targeted antimetastatic agent. 2021 Oct 5 1
4 33973637 N1-acetylspermidine is a determinant of hair follicle stem cell fate. 2021 May 1 3
5 31629858 Acrolein is involved in ischemic stroke-induced neurotoxicity through spermidine/spermine-N1-acetyltransferase activation. 2020 Jan 1
6 31911608 Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. 2020 Jan 7 2
7 32432721 Dengue virus targets RBM10 deregulating host cell splicing and innate immune response. 2020 Jul 9 1
8 32493979 Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. 2020 Jun 3 1
9 31352009 Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression. 2019 Oct 20 2
10 31362354 Liquid Biopsy in Lung Cancer Screening: The Contribution of Metabolomics. Results of A Pilot Study. 2019 Jul 29 1
11 31399646 Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness. 2019 Oct 5
12 31484073 Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication. 2019 Sep 3 1
13 29533973 Cellular and Animal Model Studies on the Growth Inhibitory Effects of Polyamine Analogues on Breast Cancer. 2018 Mar 13 2
14 29554129 Identification of aaNAT5b as a spermine N-acetyltransferase in the mosquito, Aedes aegypti. 2018 1
15 29729200 Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features. 2018 Oct 1
16 29777905 Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes. 2018 Sep 1
17 30138353 Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. 2018 1
18 30214636 Rewiring of cisplatin-resistant bladder cancer cells through epigenetic regulation of genes involved in amino acid metabolism. 2018 1
19 27901475 Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells. 2017 Jan 3 7
20 28017891 Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. 2017 Jan 28 2
21 28082202 Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism. 2017 Feb 5 2
22 28157137 Extracellular polyamines-induced proliferation and migration of cancer cells by ODC, SSAT, and Akt1-mediated pathway. 2017 Apr 4
23 28423064 Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047. 2017 2
24 28572828 Apigenin Inhibits Human SW620 Cell Growth by Targeting Polyamine Catabolism. 2017 3
25 26572277 Exogenous spermine inhibits the proliferation of human pulmonary artery smooth muscle cells caused by chemically-induced hypoxia via the suppression of the ERK1/2- and PI3K/AKT-associated pathways. 2016 Jan 2
26 26704566 Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells. 2016 Apr 3
27 27283903 Cancer-secreted AGR2 induces programmed cell death in normal cells. 2016 Aug 2 2
28 27427208 Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses. 2016 Aug 10 1
29 27535047 Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses. 2016 Nov 1 1
30 27698118 Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. 2016 Nov 1 2
31 25153488 Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer. 2015 Feb 2 1
32 25849284 Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells. 2015 Jun 15 4
33 25893668 Expression of spermidine/spermine N(1) -acetyl transferase (SSAT) in human prostate tissues is related to prostate cancer progression and metastasis. 2015 Aug 1 4
34 25959060 Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 (SAT1) gene in major depression and suicide. 2015 Jul 2
35 23701543 CDK inhibitors induce mitochondria-mediated apoptosis through the activation of polyamine catabolic pathway in LNCaP, DU145 and PC3 prostate cancer cells. 2014 1
36 23701549 A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase. 2014 4
37 23771789 Polyamine catabolism in carcinogenesis: potential targets for chemotherapy and chemoprevention. 2014 Mar 1
38 24190492 Purvalanol A is a strong apoptotic inducer via activating polyamine catabolic pathway in MCF-7 estrogen receptor positive breast cancer cells. 2014 Jan 1
39 24607957 Spermidine/spermine N(1)-acetyltransferase activity associates with white blood cell count in myeloid leukemias. 2014 Jul 1
40 24649071 Lack of evidence for the association of ornithine decarboxylase (+316 G>A), spermidine/spermine acetyl transferase (-1415 T>C) gene polymorphisms with calcium oxalate stone disease. 2014 Jan 3
41 24735382 Putative association between the -1415 T/C polymorphism of spermidine/spermine N1-acetyltransferase (SSAT1) gene and alcohol use disorders in women and men. 2014 May 1
42 25214240 Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells. 2014 Dec 1
43 25277523 The polyamine catabolic enzyme SAT1 modulates tumorigenesis and radiation response in GBM. 2014 Dec 1 3
44 25893137 Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders. 2014 4
45 23024204 Metabolism of triethylenetetramine and 1,12-diamino-3,6,9-triazadodecane by the spermidine/spermine-N(1)-acetyltransferase and thialysine acetyltransferase. 2013 Jan 1
46 23345430 Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells. 2013 Feb 5 6
47 23768751 Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour. 2013 Nov 2
48 23794266 Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression. 2013 Dec 4
49 23891576 Downregulation of the polyamine regulator spermidine/spermine N(1)-acetyltransferase by Epstein-Barr virus in a Burkitt's lymphoma cell line. 2013 Oct 1
50 23943804 Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism. 2013 Oct 2