| 1 |
33826740 | Molecular Configuration of Human Genome Neighboring Megabase-Sized Large Deletions Induced by X-Ray Irradiation. | 2021 Jun 1 |
2 |
| 2 |
33488667 | Analysis of Wild Type LbCpf1 Protein, and PAM Recognition Variants, in a Cellular Context. | 2020 |
1 |
| 3 |
28976243 | Colonic thioguanine pro-drug: Investigation of microbiome and novel host metabolism. | 2018 Mar 4 |
2 |
| 4 |
28712454 | CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions. | 2017 Aug 3 |
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| 5 |
26130722 | Enriching CRISPR-Cas9 targeted cells by co-targeting the HPRT gene. | 2015 Nov 16 |
2 |
| 6 |
24623236 | The human T-cell cloning assay: identifying genotypes susceptible to drug toxicity and somatic mutation. | 2014 |
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| 7 |
22001673 | Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. | 2012 Jan |
4 |
| 8 |
22941066 | High-throughput quantitative analysis with cell growth kinetic curves for low copy number mutant cells. | 2012 Oct |
2 |
| 9 |
21383199 | Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. | 2011 Mar 22 |
2 |
| 10 |
21798277 | The role of human cytochrome P4503A4 in biotransformation of tissue-specific derivatives of 7H-dibenzo[c,g]carbazole. | 2011 Sep 15 |
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| 11 |
20544508 | Limited intra-individual variability in hypoxanthine-Guanine phosphoribosyl transferase, thiopurine S-methyl transferase, and xanthine oxidase activity in inflammatory bowel disease patients during 6-thioguanine therapy. | 2010 Jun |
6 |
| 12 |
16293269 | Cellular and molecular effects for mutation induction in normal human cells irradiated with accelerated neon ions. | 2006 Feb 22 |
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| 13 |
17066413 | HGPRT mutation induction by N-ethyl-N-nitrosourea as measured by 6-thioguanine resistance is higher in male than in female Syrian hamster fetuses. | 2006 Oct |
4 |
| 14 |
17225873 | Real-time PCR and linkage studies to identify carriers presenting HPRT deleted gene. | 2006 Sep-Oct |
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| 15 |
15502220 | Methods for detecting somatic mutations in vitro: the human T-cell cloning assay selecting for HPRT mutants. | 2005 |
1 |
| 16 |
16195314 | Uranyl acetate induces hprt mutations and uranium-DNA adducts in Chinese hamster ovary EM9 cells. | 2005 Nov |
2 |
| 17 |
15146465 | Structural and functional analysis of mutations at the human hypoxanthine phosphoribosyl transferase (HPRT1) locus. | 2004 Jun |
2 |
| 18 |
15858385 | LET and ion-species dependence for mutation induction and mutation spectrum on hprt locus in normal human fibroblasts. | 2004 Nov |
1 |
| 19 |
14529546 | Thioguanine, mercaptopurine: their analogs and nucleosides as antimetabolites. | 2003 |
1 |
| 20 |
14676365 | LET and ion-species dependence for cell killing and mutation induction in normal human fibroblasts. | 2003 Oct |
1 |
| 21 |
15136753 | Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells. | 2003 Dec |
1 |
| 22 |
11756148 | Frequent detection of T cells with mutations of the hypoxanthine-guanine phosphoribosyl transferase gene in patients with paroxysmal nocturnal hemoglobinuria. | 2002 Jan 1 |
5 |
| 23 |
11827715 | Aphidicolin induces 6-thioguanine resistant mutants in human diploid fibroblasts. | 2002 Feb 20 |
2 |
| 24 |
12428919 | Mutagenicity of low-filtered 30 kVp X-rays, mammography X-rays and conventional X-rays in cultured mammalian cells. | 2002 Sep |
1 |
| 25 |
11239972 | Analysis of mutational effects at the HPRT locus in human G(0) phase lymphocytes irradiated in vitro with gamma rays. | 2001 Mar 1 |
1 |
| 26 |
11698345 | Mutational spectrum induced by acetaldehyde in the HPRT gene of human T lymphocytes resembles that in the p53 gene of esophageal cancers. | 2001 Nov |
1 |
| 27 |
10719032 | Combined effects of gamma-radiation and ethylene oxide in human diploid fibroblasts. | 2000 Mar |
1 |
| 28 |
10728688 | The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells. | 2000 Mar 1 |
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| 29 |
10839990 | A new method for the selection of protein interactions in mammalian cells. | 2000 Jun 15 |
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| 30 |
10849375 | Azathioprine associated T-cell mutations in insulin-dependent diabetes mellitus. | 2000 Jun |
4 |
| 31 |
10365782 | Elimination of non-viable 6-thioguanine-sensitive T cells from viable T cells prior to PCR analysis. | 1999 May 27 |
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| 32 |
10635988 | Validation of the human T-lymphocyte cloning assay--ring test report from the EU concerted action on HPRT mutation (EUCAHM). | 1999 Dec 17 |
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| 33 |
10635989 | Bromodeoxyuridine labelling as an alternative method to identify 6-thioguanine-resistant mutant lymphocytes in humans. | 1999 Dec 17 |
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| 34 |
10635993 | Analysis of point mutations in HPRT mutant T-lymphocytes derived from coke-oven workers. | 1999 Dec 17 |
2 |
| 35 |
10636001 | Analysis of oxidative DNA damage and HPRT mutant frequencies in cancer patients before and after radiotherapy. | 1999 Dec 17 |
2 |
| 36 |
10636005 | Spontaneous and chemically induced point mutations in HPRT cDNA of the metabolically competent human lymphoblastoid cell line, MCL-5. | 1999 Dec 17 |
2 |
| 37 |
9598152 | Measurement of mutation frequency at the HPRT locus in peripheral lymphocytes. Is this a good method to evaluate a cancer risk in pediatric patients? | 1998 |
2 |
| 38 |
9600338 | Spectrum of point mutations in the coding region of the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene in human T-lymphocytes in vivo. | 1998 Apr |
4 |
| 39 |
9626969 | Frequency of HPRT gene mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine corresponds to replication error phenotypes of cell lines. | 1998 Feb 26 |
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| 40 |
9855005 | Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus. | 1998 Nov |
2 |
| 41 |
9920053 | Rapid characterization of mutations in amplified human hprt cDNA by polyacrylamide gel electrophoresis. | 1998 Nov |
1 |
| 42 |
9049058 | Nitrogen mustard-mediated mutagenesis in human T-lymphocytes in vitro. | 1997 |
3 |
| 43 |
9054586 | Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line. | 1997 Jan |
1 |
| 44 |
9092930 | Mutagenic activity of high-energy 532 nm ultra-short laser pulses. | 1997 Apr |
2 |
| 45 |
9187113 | Increased genetic stability of HeLa cells after connexin 43 gene transfection. | 1997 Jun 1 |
1 |
| 46 |
9399700 | Comparisons of the frequencies and molecular spectra of HPRT mutants when human cancer cells were X-irradiated during G1 or S phase. | 1997 Dec |
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| 47 |
8876696 | Mutational spectra vary with exposure conditions: benzo[a]pyrene in human cells. | 1996 Oct 25 |
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| 48 |
8921909 | Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting. | 1996 Oct 31 |
2 |
| 49 |
9000176 | Isolation and characterization of HPRT-deficient human hepatoma cells. | 1996 Jul |
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| 50 |
7477056 | Frequency of HPRT mutant lymphocytes in a human control population as determined by the T-cell cloning procedure. | 1995 Oct |
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