Title : Analysis of point mutations in HPRT mutant T-lymphocytes derived from coke-oven workers.

Pub. Date : 1999 Dec 17

PMID : 10635993






2 Functional Relationships(s)
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1 We studied mutations in exon 3 of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in 113 6-thioguanine-resistant T-cell clones derived from coke-oven workers and control subjects in order to analyse possible changes in the mutational spectrum associated with the exposure to polycyclic aromatic hydrocarbons (PAHs). Thioguanine hypoxanthine phosphoribosyltransferase 1 Homo sapiens
2 We studied mutations in exon 3 of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in 113 6-thioguanine-resistant T-cell clones derived from coke-oven workers and control subjects in order to analyse possible changes in the mutational spectrum associated with the exposure to polycyclic aromatic hydrocarbons (PAHs). Thioguanine hypoxanthine phosphoribosyltransferase 1 Homo sapiens