Cocaine

solute carrier family 6 member 3 ; Homo sapiens







327 Article(s)
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1 34906999 Allosteric Modulator KM822 Attenuates Behavioral Actions of Amphetamine in Caenorhabditis elegans through Interactions with the Dopamine Transporter DAT-1. 2022 Mar 5
2 32859997 D-amphetamine maintenance treatment goes a long way: lasting therapeutic effects on cocaine behavioral effects and cocaine potency at the dopamine transporter. 2021 Jan 1
3 32956676 The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology. 2021 Feb 1 1
4 33446713 A study of the dopamine transporter using the TRACT assay, a novel in vitro tool for solute carrier drug discovery. 2021 Jan 14 1
5 33610553 Direct coupling of oligomerization and oligomerization-driven endocytosis of the dopamine transporter to its conformational mechanics and activity. 2021 Jan-Jun 1
6 33785354 Functional characterization of N-octyl 4-methylamphetamine variants and related bivalent compounds at the dopamine and serotonin transporters using Ca2+ channels as sensors. 2021 May 15 1
7 33803578 Distinct Regulation of Dopamine D3 Receptor in the Basolateral Amygdala and Dentate Gyrus during the Reinstatement of Cocaine CPP Induced by Drug Priming and Social Stress. 2021 Mar 18 2
8 33888022 An efficient and label-free LC-MS/MS method for assessing drug's activity at dopamine and serotonin transporters using transporter-transfected HEK293T cells. 2021 Jun 1
9 34015332 Optogenetically-induced multimerization of the dopamine transporter increases uptake and trafficking to the plasma membrane. 2021 Jan-Jun 2
10 34199621 Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter. 2021 Jun 2 2
11 34420294 Toward Reducing hERG Affinities for DAT Inhibitors with a Combined Machine Learning and Molecular Modeling Approach. 2021 Sep 27 3
12 34619165 Non-conserved residues dictate dopamine transporter selectivity for the potent synthetic cathinone and psychostimulant MDPV. 2021 Dec 1 2
13 34752088 Proteome-Informed Machine Learning Studies of Cocaine Addiction. 2021 Nov 18 1
14 31828739 How Important Is the Use of Cocaine and Amphetamines in the Development of Parkinson Disease? A Computational Study. 2020 Mar 1
15 32132171 Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. 2020 Apr 17 1
16 30125594 Identification of the benztropine analog [125I]GA II 34 binding site on the human dopamine transporter. 2019 Feb 1
17 30284596 Effects of MDPV on dopamine transporter regulation in male rats. Comparison with cocaine. 2019 Mar 3
18 30828290 The SUMO-Conjugase Ubc9 Prevents the Degradation of the Dopamine Transporter, Enhancing Its Cell Surface Level and Dopamine Uptake. 2019 1
19 30981746 Effects of stimulant drug use on the dopaminergic system: A systematic review and meta-analysis of in vivo neuroimaging studies. 2019 Jun 1
20 31009648 Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT). 2019 Jun 15 2
21 31184115 Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter. 2019 Aug 21 2
22 31660902 Dynamic interaction of genetic risk factors and cocaine abuse in the background of Parkinsonism - a case report. 2019 Oct 28 1
23 28734904 Identifying novel members of the Wntless interactome through genetic and candidate gene approaches. 2018 Apr 1
24 29421542 Leptin levels and its correlation with crack-cocaine use severity: A preliminary study. 2018 Apr 3 1
25 29965988 Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation. 2018 1
26 30033547 Methylation of the dopamine transporter gene in blood is associated with striatal dopamine transporter availability in ADHD: A preliminary study. 2018 Aug 2
27 30042675 A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336. 2018 1
28 30305739 The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter. 2018 Nov 1
29 27789280 Regional influence of cocaine on evoked dopamine release in the nucleus accumbens core: A role for the caudal brainstem. 2017 Jan 15 2
30 28441487 The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation. 2017 Aug 16 2
31 28623359 Allosteric modulatory effects of SRI-20041 and SRI-30827 on cocaine and HIV-1 Tat protein binding to human dopamine transporter. 2017 Jun 16 1
32 28710426 Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter. 2017 Jul 14 3
33 28734204 Molecular dynamics of conformation-specific dopamine transporter-inhibitor complexes. 2017 Sep 4
34 28734777 Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs. 2017 Oct 15 6
35 28847807 The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach. 2017 Sep 27 2
36 28894302 Gβγ subunit activation promotes dopamine efflux through the dopamine transporter. 2017 Dec 1
37 29091428 Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors. 2017 Nov 22 1
38 29332099 Association between the Intron 8 VNTR Polymorphism of the DAT1 Gene and Crack Cocaine Addiction. 2017 1
39 26892922 Dopamine Transporter Correlates and Occupancy by Modafinil in Cocaine-Dependent Patients: A Controlled Study With High-Resolution PET and [(11)C]-PE2I. 2016 Aug 1
40 27018734 Enhanced Dopamine Release by Dopamine Transport Inhibitors Described by a Restricted Diffusion Model and Fast-Scan Cyclic Voltammetry. 2016 Jun 15 1
41 27187231 Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels. 2016 May 17 2
42 27555326 Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells. 2016 Oct 14 1
43 27833323 Tc-99m TRODAT uptake in an osteoid tumor of clivus. 2016 Oct-Dec 1
44 25212486 Brief intermittent cocaine self-administration and abstinence sensitizes cocaine effects on the dopamine transporter and increases drug seeking. 2015 Feb 7
45 25580950 Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities. 2015 Apr 2
46 25644383 DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. 2015 Dec 1
47 25689882 A Single Amphetamine Infusion Reverses Deficits in Dopamine Nerve-Terminal Function Caused by a History of Cocaine Self-Administration. 2015 Jul 2
48 25747272 Single-quantum-dot tracking reveals altered membrane dynamics of an attention-deficit/hyperactivity-disorder-derived dopamine transporter coding variant. 2015 Apr 15 2
49 25749646 Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding. 2015 Sep 1
50 25772534 Cooperativity between individual transporter protomers: new data fuelling old complexes. 2015 Apr 1