Title : The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter.

Pub. Date : 2018 Nov

PMID : 30305739






1 Functional Relationships(s)
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1 Uptake inhibition assays in rat brain synaptosomes were used to directly compare the potency of MDPV, MDPBP, MDPPP, alpha-PVP, alpha-PPP, and cocaine at DAT, NET, and SERT, whereas intravenous self-administration in rats was used to quantify relative reinforcing effectiveness of the drugs using progressive ratio (PR) and behavioral economic procedures. Cocaine solute carrier family 6 member 3 Homo sapiens