Metformin

vascular endothelial growth factor A ; Homo sapiens







34 Article(s)
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1 35139776 Metformin attenuates high glucose-induced injury in islet microvascular endothelial cells. 2022 Feb 3
2 34238029 Metformin Antagonizes Ovarian Cancer Cells Malignancy Through MSLN Mediated IL-6/STAT3 Signaling. 2021 Jan-Dec 2
3 32452405 Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia. 2020 Jun 1
4 33049108 Metformin enhances osteogenic differentiation of stem cells from human exfoliated deciduous teeth through AMPK pathway. 2020 Dec 1
5 33081077 Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells. 2020 Oct 16 1
6 30575815 Endothelial fatty liver binding protein 4: a new targetable mediator in hepatocellular carcinoma related to metabolic syndrome. 2019 Apr 1
7 30710234 Anti-proliferative and anti-apoptotic potential effects of epigallocatechin-3-gallate and/or metformin on hepatocellular carcinoma cells: in vitro study. 2019 Apr 1
8 31002375 [Corrigendum] Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo. 2019 Jun 1
9 31120617 RasGRP1 is a target for VEGF to induce angiogenesis and involved in the endothelial-protective effects of metformin under high glucose in HUVECs. 2019 Sep 3
10 29670840 Investigating Effect of Rapamycin and Metformin on Angiogenesis in Hepatocellular Carcinoma Cell Line. 2018 Mar 1
11 29678660 Metformin combined with quercetin synergistically repressed prostate cancer cells via inhibition of VEGF/PI3K/Akt signaling pathway. 2018 Jul 20 3
12 30272364 Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo. 2018 Dec 4
13 30372835 Prolonged incubation with Metformin decreased angiogenic potential in human bone marrow mesenchymal stem cells. 2018 Dec 1
14 28427181 Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK. 2017 May 16 1
15 29344202 Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2. 2017 Dec 1
16 26305116 Metformin inhibits proliferation and proinflammatory cytokines of human keratinocytes in vitro via mTOR-signaling pathway. 2016 Jul 1
17 26861446 Metformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction. 2016 Feb 9 3
18 27378194 Metformin use and gynecological cancers: A novel treatment option emerging from drug repositioning. 2016 Sep 1
19 25179820 The anti-diabetic drug metformin inhibits vascular endothelial growth factor expression via the mammalian target of rapamycin complex 1/hypoxia-inducible factor-1α signaling pathway in ELT-3 cells. 2015 Jan 5 1
20 25785990 Anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy is mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1. 2015 1
21 25981877 Metformin as possible therapy of pulmonary arterio venous malformation in HHT patients. 2015 Sep 1
22 26260219 Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models. 2015 Oct 2
23 26625311 Suppression of tumor angiogenesis by metformin treatment via a mechanism linked to targeting of HER2/HIF-1α/VEGF secretion axis. 2015 Dec 29 4
24 24419232 Paradoxic effects of metformin on endothelial cells and angiogenesis. 2014 May 3
25 23225247 Metformin inhibits advanced glycation end products (AGEs)-induced growth and VEGF expression in MCF-7 breast cancer cells by suppressing AGEs receptor expression via AMP-activated protein kinase. 2013 May 6
26 23526220 Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway. 2013 Aug 1
27 23879009 [Metformin--new treatment strategies for gynecologic neoplasms]. 2013 1
28 24011132 Metformin decreases the incidence of ovarian hyperstimulation syndrome: an experimental study. 2013 Sep 8 1
29 22469973 Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathway. 2012 Jun 2
30 22576211 Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A. 2012 Apr 2
31 23653852 Anti-angiogenic Effects of Metformin, an AMPK Activator, on Human Umbilical Vein Endothelial Cells and on Granulation Tissue in Rat. 2012 Nov 1
32 21532889 Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo. 2011 May 1
33 18256928 Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. 2009 Jan 3
34 18358555 The effect of metformin treatment on VEGF and PAI-1 levels in obese type 2 diabetic patients. 2008 Jul 4