Doxorubicin

ATP-binding cassette, sub-family B (MDR/TAP), member 1B ; Mus musculus







52 Article(s)
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1 31729540 In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance. 2020 Jul 1
2 32159961 Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles. 2020 Apr 6 2
3 32392918 Oncogenic Ras downregulates mdr1b expression through generation of reactive oxygen species. 2020 May 1 1
4 32395078 Oncogenic Ras downregulates mdr1b expression through generation of reactive oxygen species. 2020 May 1 1
5 30221549 siRNAs targeting multidrug transporter genes sensitise breast tumour to doxorubicin in a syngeneic mouse model. 2019 Mar 2
6 28681913 Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR. 2018 Apr 1
7 29462422 Multidrug Resistance Protein 1 Deficiency Promotes Doxorubicin-Induced Ovarian Toxicity in Female Mice. 2018 May 1 3
8 27760838 Identification and Validation of Compounds Selectively Killing Resistant Cancer: Delineating Cell Line-Specific Effects from P-Glycoprotein-Induced Toxicity. 2017 Jan 2
9 27777271 Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance. 2017 Jan 2
10 28624193 MiR-375 and Doxorubicin Co-delivered by Liposomes for Combination Therapy of Hepatocellular Carcinoma. 2017 Jun 16 2
11 26824187 A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function. 2016 Feb 23 1
12 27272776 siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma. 2016 Jun 1
13 25385827 Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts. 2015 Jan 2
14 25915534 Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter. 2015 Jun 20 2
15 26075272 Ecdysteroids sensitize MDR and non-MDR cancer cell lines to doxorubicin, paclitaxel, and vincristine but tend to protect them from cisplatin. 2015 3
16 26194248 Effect of Knockout of Mdr1a and Mdr1b ABCB1 Genes on the Systemic Exposure of a Doxorubicin-Conjugated Block Copolymer in Mice. 2015 Sep 8 5
17 24858827 Reversal of multidrug resistance in vitro and in vivo by 5-N-formylardeemin, a new ardeemin derivative. 2014 Aug 1
18 22820863 Conditionally replicative adenovirus-based mda-7/IL-24 expression enhances sensitivity of colon cancer cells to 5-fluorouracil and doxorubicin. 2013 Feb 1
19 22704597 Overcoming multidrug resistance by co-delivery of Mdr-1 and survivin-targeting RNA with reduction-responsible cationic poly(β-amino esters). 2012 Sep 2
20 21965738 Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis. 2011 Oct 1
21 20642825 Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1. 2010 Jul 19 1
22 19654309 Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer. 2009 Aug 15 2
23 18722489 Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant. 2008 Nov 12 1
24 17407711 [Reversal of adriamycin resistance of hepatocellular carcinoma by targeting it with recombined adenovirus carrying antisense multidrug resistance gene 1 RNA]. 2007 Mar 1
25 16568009 [Anti-tumor immunotherapy against multidrug resistance]. 2006 Mar 1
26 15725475 Establishment and characterization of new cellular lymphoma model expressing transgenic human MDR1. 2005 Apr 1
27 15826724 Increase of doxorubicin sensitivity by doxorubicin-loading into nanoparticles for hepatocellular carcinoma cells in vitro and in vivo. 2005 May 1
28 16101136 Inhibition of P-glycoprotein transport activity in a resistant mouse lymphoma cell line by diterpenic lactones. 2005 Sep-Oct 1
29 14962730 Inhibition of multidrug resistance by immunisation with synthetic P-glycoprotein-derived peptides. 2004 Mar 1
30 15449049 In vitro detection of mdr1 mRNA in murine leukemia cells with 111In-labeled oligonucleotide. 2004 Nov 1
31 14552591 Development of a syngeneic in vivo tumor model and its use in evaluating a novel P-glycoprotein modulator, PGP-4008. 2003 2
32 11235562 [Protection of hematopoietic cells against toxicity of anticancer agents by transfecting mdr1 gene into bone marrow cells]. 2000 Nov 1
33 9525472 Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells. 1998 May 1
34 9698071 A unique interaction between polyamine and multidrug resistance (P-glycoprotein) transporters in cultured Chinese hamster ovary cells transfected with mouse mdr-1 gene. 1998 Jul 15 1
35 9866690 Identification of multidrug resistant protein 1 of mouse leukemia P388 cells on a PVDF membrane using 6-aminoquinolyl-carbamyl (AQC)-amino acid analysis and World Wide Web (WWW)-accessible tools. 1998 Nov 15 5
36 9010037 Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia. 1997 1
37 9272128 Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. 1997 1
38 9542528 Maintenance of hypomethylation status and preferential expression of exogenous human MDR1/PGY1 gene in mouse L cells by YAC mediated transfer. 1997 Jul 1
39 8611717 Cure of multidrug-resistant human B-cell lymphoma xenografts by combinations of anti-B4-blocked ricin and chemotherapeutic drugs. 1996 May 1 1
40 8650203 Functional expression of mouse Mdr1 in an outer membrane permeability mutant of Escherichia coli. 1996 Jun 11 1
41 7896537 Reversal of multidrug resistance in murine fibrosarcoma cells by thioxanthene flupentixol. 1994 1
42 7909724 Dominant expression of multidrug resistance in intraspecific murine lymphoma hybrid cells. 1994 2
43 7910854 Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. 1994 Jun 15 1
44 8103679 Modulatory effects on substrate specificity of independent mutations at the serine939/941 position in predicted transmembrane domain 11 of P-glycoproteins. 1993 Sep 14 1
45 1363885 Down-regulation of ras and myc expression associated with mdr-1 overexpression in adriamycin-resistant tumor cells. 1992 Sep 1
46 1676579 Time course of MDR gene amplification during in vivo selection for doxorubicin-resistance and during reversal in murine leukemia L 1210. 1991 Mar-Apr 2
47 1678520 A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps. 1991 Aug 15 2
48 1868977 Molecular manipulations of the multidrug transporter: a new role for transgenic mice. 1991 Aug 1
49 1968358 Cellular and biochemical characterization of thioxanthenes for reversal of multidrug resistance in human and murine cell lines. 1990 Mar 15 1
50 1983720 Structure and function of P-glycoprotein in the normal liver and intestine. 1990 2