Title : Molecular manipulations of the multidrug transporter: a new role for transgenic mice.

Pub. Date : 1991 Aug

PMID : 1868977






1 Functional Relationships(s)
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Protein Name
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1 Transgenic mice that express the MDR1 gene in their bone marrow have been developed, and because of this expression these mice are resistant to the bone marrow-suppressive effects of daunomycin, doxorubicin, taxol, and several other anticancer drugs. Doxorubicin ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus