| 1 |
32238854 | Immunomodulatory drugs activate NK cells via both Zap-70 and cereblon-dependent pathways. | 2021 Jan |
2 |
| 2 |
33562083 | A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling. | 2021 Feb 6 |
1 |
| 3 |
34394081 | Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse. | 2021 |
1 |
| 4 |
34413312 | Integration of FRET and sequencing to engineer kinase biosensors from mammalian cell libraries. | 2021 Aug 19 |
2 |
| 5 |
34414199 | Downregulation of CD45 Signaling in COVID-19 Patients Is Reversed by C24D, a Novel CD45 Targeting Peptide. | 2021 |
1 |
| 6 |
34960785 | Hepatitis C Virus Core Protein Down-Regulates Expression of Src-Homology 2 Domain Containing Protein Tyrosine Phosphatase by Modulating Promoter DNA Methylation. | 2021 Dec 15 |
1 |
| 7 |
31964936 | Profiling of human lymphocytes reveals a specific network of protein kinases modulated by endurance training status. | 2020 Jan 21 |
1 |
| 8 |
32469452 | PTPN22 interacts with EB1 to regulate T-cell receptor signaling. | 2020 Jul |
1 |
| 9 |
29789296 | Tuning ITAM multiplicity on T cell receptors can control potency and selectivity to ligand density. | 2018 May 22 |
1 |
| 10 |
30372858 | Exploration of the therapeutic aspects of Lck: A kinase target in inflammatory mediated pathological conditions. | 2018 Dec |
1 |
| 11 |
28415650 | A highly conserved redox-active Mx(2)CWx(6)R motif regulates Zap70 stability and activity. | 2017 May 9 |
1 |
| 12 |
25316710 | SRC homology 2 domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) N-terminal tyrosine residues regulate a dynamic signaling equilibrium involving feedback of proximal T-cell receptor (TCR) signaling. | 2015 Jan |
1 |
| 13 |
25682964 | The function of a novel immunophenotype candidate molecule PD-1 in chronic lymphocytic leukemia. | 2015 |
1 |
| 14 |
25800872 | Intracellular cytoplasm-specific delivery of SH3 and SH2 domains of SLAP inhibits TcR-mediated signaling. | 2015 May 8 |
1 |
| 15 |
25990959 | The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. | 2015 May 19 |
3 |
| 16 |
26043137 | Vav1 Regulates T-Cell Activation through a Feedback Mechanism and Crosstalk between the T-Cell Receptor and CD28. | 2015 Jul 2 |
1 |
| 17 |
24256567 | Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants. | 2014 Feb |
2 |
| 18 |
22898186 | ZAP-70 tyrosines 315 and 492 transmit non-genomic glucocorticoid (GC) effects in T cells. | 2013 Jan |
4 |
| 19 |
23124046 | Identification of a novel mutation in ZAP70 and prenatal diagnosis in a Turkish family with severe combined immunodeficiency disorder. | 2013 Jan 10 |
1 |
| 20 |
23530057 | Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. | 2013 Jun |
7 |
| 21 |
23874979 | ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. | 2013 |
1 |
| 22 |
23880762 | Mitochondria-derived hydrogen peroxide selectively enhances T cell receptor-initiated signal transduction. | 2013 Sep 6 |
1 |
| 23 |
24204825 | Quantitative phosphoproteome analysis unveils LAT as a modulator of CD3ΞΆ and ZAP-70 tyrosine phosphorylation. | 2013 |
1 |
| 24 |
22207134 | Fine-tuning of proximal TCR signaling by ZAP-70 tyrosine residues in Jurkat cells. | 2012 Feb |
1 |
| 25 |
21393235 | Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways. | 2011 May 6 |
1 |
| 26 |
21463338 | Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression. | 2011 Aug |
1 |
| 27 |
21725281 | Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells. | 2011 Jul 1 |
1 |
| 28 |
21757751 | A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase. | 2011 Sep 2 |
2 |
| 29 |
20682913 | The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling. | 2010 Aug 3 |
1 |
| 30 |
19168706 | T-cell receptor signaling is mediated by transient Lck activity, which is inhibited by inorganic mercury. | 2009 Jun |
1 |
| 31 |
19290920 | The structure, regulation, and function of ZAP-70. | 2009 Mar |
2 |
| 32 |
19605366 | A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. | 2009 Nov |
1 |
| 33 |
18287138 | Clonal heterogeneity in chronic lymphocytic leukemia cells: superior response to surface IgM cross-linking in CD38, ZAP-70-positive cells. | 2008 Mar |
1 |
| 34 |
18432193 | Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. | 2008 Jun 12 |
1 |
| 35 |
18548611 | Intracellular Phospho-Flow cytometry reveals novel insights into TCR proximal signaling events. A comparison with Western blot. | 2008 Sep |
3 |
| 36 |
17038529 | ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. | 2007 Mar 1 |
1 |
| 37 |
17222799 | Intermolecular relations between the glucocorticoid receptor, ZAP-70 kinase, and Hsp-90. | 2007 Mar 2 |
1 |
| 38 |
17250586 | CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor. | 2007 Apr |
6 |
| 39 |
17512407 | Structural basis for the inhibition of tyrosine kinase activity of ZAP-70. | 2007 May 18 |
2 |
| 40 |
17579062 | Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains. | 2007 Jul 1 |
1 |
| 41 |
18092677 | [Identification of a functional ITAM-like sequence within G1 cytoplasmic tail of Hantaan virus]. | 2007 Nov |
1 |
| 42 |
16406604 | Dexamethasone induces rapid tyrosine-phosphorylation of ZAP-70 in Jurkat cells. | 2006 Feb |
2 |
| 43 |
16461343 | Identification of substrates of human protein-tyrosine phosphatase PTPN22. | 2006 Apr 21 |
5 |
| 44 |
16984412 | Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing suppressor of cytokine signalling-1 (SOCS-1). | 2006 Oct |
2 |
| 45 |
15572591 | Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. | 2005 Mar 15 |
1 |
| 46 |
15749915 | B cell response to surface IgM cross-linking identifies different prognostic groups of B-chronic lymphocytic leukemia patients. | 2005 Mar 15 |
1 |
| 47 |
15832176 | Role of p56lck and ZAP70-mediated tyrosine phosphorylation in galectin-1-induced cell death. | 2005 Aug |
1 |
| 48 |
16049944 | Determination of regulatory phosphorylation sites in nanogram amounts of a synthetic fragment of ZAP-70 using microprobe NMR and on-line coupled capillary HPLC-NMR. | 2005 Sep |
2 |
| 49 |
16081816 | Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways. | 2005 Aug 15 |
2 |
| 50 |
16151467 | Imatinib mesylate suppresses cytokine synthesis by activated CD4 T cells of patients with chronic myelogenous leukemia. | 2005 Nov |
1 |