Title : The function of a novel immunophenotype candidate molecule PD-1 in chronic lymphocytic leukemia.

Pub. Date : 2015

PMID : 25682964






1 Functional Relationships(s)
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1 We demonstrated that phosphorylation of SYK and LYN, key B-cell receptor signaling kinases, was independent of PD-1 expression in patients with CLL, while ZAP-70 phosphorylation in negative tyrosine residue 292 showed strong inverse correlation (r = - 0.8, p = 0.0019). Tyrosine zeta chain of T cell receptor associated protein kinase 70 Homo sapiens