| 1 |
27974382 | Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities. | 2017 Mar |
1 |
| 2 |
22486895 | Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol. | 2012 May 30 |
1 |
| 3 |
22700965 | Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes. | 2012 Aug 3 |
1 |
| 4 |
21473878 | Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach. | 2011 Jun 1 |
3 |
| 5 |
21680215 | Computational insights into the different catalytic activities of CYP2A13 and CYP2A6 on NNK. | 2011 Sep |
2 |
| 6 |
21475870 | 8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. | 2009 Jul-Aug |
3 |
| 7 |
19029401 | Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer. | 2008 Dec |
2 |
| 8 |
17178771 | CYP2A13 metabolizes the substrates of human CYP1A2, phenacetin, and theophylline. | 2007 Mar |
1 |
| 9 |
17717079 | Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes. | 2007 Nov |
1 |
| 10 |
15893417 | Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice. | 2006 Mar 28 |
1 |
| 11 |
16176798 | Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. | 2005 Dec 9 |
2 |
| 12 |
15544431 | Cigarette smoking, metabolic activation and carcinogenesis. | 2004 Oct |
1 |
| 13 |
14633670 | Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice. | 2003 Nov 15 |
3 |
| 14 |
11805739 | Genetic variation in CYP2A6-mediated nicotine metabolism alters smoking behavior. | 2002 Feb |
1 |
| 15 |
12115524 | Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma. | 2002 Aug 1 |
2 |
| 16 |
11241319 | Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. | 2001 Mar 20 |
1 |
| 17 |
11259349 | Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk. | 2001 Apr |
2 |
| 18 |
10999944 | Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking. | 2000 Oct |
1 |
| 19 |
10441482 | CYP2A6 gene deletion reduces susceptibility to lung cancer. | 1999 Aug 11 |
2 |
| 20 |
8001247 | Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): mutational specificity in the gpt gene of AS52 cells. | 1994 Dec |
2 |
| 21 |
8022436 | N-nitrosodiethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced morphological transformation of C3H/10T1/2CL8 cells expressing human cytochrome P450 2A6. | 1994 Jul |
2 |
| 22 |
8330360 | Retroviral mediated expression of human cytochrome P450 2A6 in C3H/10T1/2 cells confers transformability by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). | 1993 Jul |
2 |