Pub. Date : 2004 Oct
PMID : 15544431
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, in our recent study, it was also shown that cigarette smoke exposure induces hepatic CYP2A8 in hamsters, which is homologous to CYP2A6 in human, and hepatic S9 fraction exposed to cigarette smoke increases the mutagenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco specific nitrosamine, which is in line with the fact that NNK is metabolically activated by CYP2A6. | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |