| 151 |
21939466 | Unraveling the glioma epigenome: from molecular mechanisms to novel biomarkers and therapeutic targets. | 2011 Nov |
1 |
| 152 |
22002076 | Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target. | 2011 Dec |
2 |
| 153 |
22040412 | Virtual mutagenesis of isocitrate dehydrogenase 1 involved in glioblastoma multiforme. | 2011 Sep |
2 |
| 154 |
22101433 | Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. | 2011 Nov 20 |
2 |
| 155 |
22147457 | [IDH1/2 mutations in gliomas]. | 2011 Dec |
2 |
| 156 |
20127344 | The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. | 2010 Apr |
1 |
| 157 |
20142433 | Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. | 2010 Feb 15 |
2 |
| 158 |
20171147 | The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. | 2010 Mar 16 |
1 |
| 159 |
20510884 | Glioma-derived mutations in IDH: from mechanism to potential therapy. | 2010 Jun 25 |
3 |
| 160 |
20603105 | IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. | 2010 Jul 30 |
1 |
| 161 |
20692206 | IDH mutations in glioma and acute myeloid leukemia. | 2010 Sep |
4 |
| 162 |
20972461 | Cancer-associated IDH mutations: biomarker and therapeutic opportunities. | 2010 Dec 9 |
1 |
| 163 |
20975740 | Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. | 2010 Nov |
1 |
| 164 |
21045145 | Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | 2010 Nov 15 |
4 |
| 165 |
19359588 | Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. | 2009 Apr 10 |
1 |
| 166 |
19935646 | Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. | 2009 Dec 10 |
2 |
| 167 |
8608121 | Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: a catalytic trigger for isocitrate dehydrogenase. | 1996 Mar 5 |
2 |
| 168 |
8369301 | Structure of isocitrate dehydrogenase with alpha-ketoglutarate at 2.7-A resolution: conformational changes induced by decarboxylation of isocitrate. | 1993 Sep 14 |
3 |