Title : The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Pub. Date : 2010 Mar 16

PMID : 20171147






1 Functional Relationships(s)
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1 The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Ketoglutaric Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens