| 1 |
35450359 | Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors. | 2022 Apr 14 |
1 |
| 2 |
33910646 | Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness. | 2021 Apr 28 |
1 |
| 3 |
31548295 | Blockade of Glutathione Metabolism in IDH1-Mutated Glioma. | 2020 Jan |
5 |
| 4 |
32312817 | Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. | 2020 May 5 |
3 |
| 5 |
32709039 | Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS. | 2020 Jul 17 |
1 |
| 6 |
32729927 | An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity. | 2020 Aug 28 |
2 |
| 7 |
33115694 | GSH and GABA decreases in IDH1-mutated low-grade gliomas detected by HERMES spectral editing at 3 T in vivo. | 2020 Dec |
3 |
| 8 |
30857299 | Consequences of IDH1/2 Mutations in Gliomas and an Assessment of Inhibitors Targeting Mutated IDH Proteins. | 2019 Mar 9 |
1 |
| 9 |
31591388 | The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis. | 2019 Oct 7 |
1 |
| 10 |
29537891 | Wild-Type Isocitrate Dehydrogenase 1 Over-Expression is Related to Cancer Stem Cells Survival in Lung Adenocarcinoma. | 2018 Mar 16 |
1 |
| 11 |
29662077 | Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate. | 2018 Apr 16 |
1 |
| 12 |
29923039 | NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione. | 2018 Aug |
1 |
| 13 |
27923831 | Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis. | 2017 Feb 15 |
1 |
| 14 |
28052098 | IDH1 R132H Mutation Enhances Cell Migration by Activating AKT-mTOR Signaling Pathway, but Sensitizes Cells to 5-FU Treatment as NADPH and GSH Are Reduced. | 2017 |
5 |
| 15 |
28564604 | Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. | 2017 May 30 |
1 |
| 16 |
29054837 | Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways. | 2017 Dec |
1 |
| 17 |
26970248 | MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T. | 2016 Oct |
1 |
| 18 |
25283382 | Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation. | 2015 Feb |
4 |
| 19 |
24362902 | An IDH1 mutation inhibits growth of glioma cells via GSH depletion and ROS generation. | 2014 Jun |
2 |
| 20 |
23801081 | Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death. | 2013 Nov |
7 |
| 21 |
22015945 | Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. | 2012 Mar |
1 |
| 22 |
22264756 | Expression of cytosolic NADP(+)-dependent isocitrate dehydrogenase in melanocytes and its role as an antioxidant. | 2012 Feb |
3 |
| 23 |
21289278 | Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. | 2011 Feb 22 |
1 |
| 24 |
19106211 | Role of cytosolic NADP+-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney. | 2009 Mar |
2 |
| 25 |
19291592 | Glutathionylation regulates cytosolic NADP+-dependent isocitrate dehydrogenase activity. | 2009 Apr |
1 |