Title : Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy.

Pub. Date : 2012 Mar

PMID : 22015945






1 Functional Relationships(s)
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1 Compared with wild-type tumors, those with IDH1 mutations had elevated choline (P = 0.01) and decreased glutathione (P = 0.03) on MRS. Glutathione isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens