Title : NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione.

Pub. Date : 2018 Aug

PMID : 29923039






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Glutathione, a cellular sulphydryl reductant, has a moderate affinity for Cd2+, allowing IDH to be activated with residual Cd2+, unlike dithiothreitol, which has a much higher affinity. Glutathione isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens