Pub. Date : 2015 Feb
PMID : 25283382
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation. | Glutathione | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 2 | The IDH1-R132H-induced higher chemosensitivity was associated with nicotine adenine disphosphonucleotide (NADPH), glutathione (GSH) depletion, and reactive oxygen species (ROS) generation. | Glutathione | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 3 | The IDH1-R132H-induced higher chemosensitivity was associated with nicotine adenine disphosphonucleotide (NADPH), glutathione (GSH) depletion, and reactive oxygen species (ROS) generation. | Glutathione | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 4 | Accordingly, this IDH1-R132H-induced growth inhibition was effectively abrogated by GSH in vitro and in vivo. | Glutathione | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |