Reactive Oxygen Species

isocitrate dehydrogenase (NADP(+)) 1 ; Homo sapiens







20 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33535038 An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism. 2021 Feb 2 2
2 33810170 Energy Metabolism in IDH1 Wild-Type and IDH1-Mutated Glioblastoma Stem Cells: A Novel Target for Therapy? 2021 Mar 22 2
3 31548295 Blockade of Glutathione Metabolism in IDH1-Mutated Glioma. 2020 Jan 1
4 32312817 Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. 2020 May 5 2
5 30639360 Oxalomalate reduces tumor progression in melanoma via ROS-dependent proapoptotic and antiangiogenic effects. 2019 Mar 1
6 30720071 Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain. 2019 Apr 1
7 31020875 Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS. 2019 Apr 4
8 31462501 Inhibition of NR4A1 Promotes ROS Accumulation and IL24-Dependent Growth Arrest in Rhabdomyosarcoma. 2019 Nov 1
9 29448107 Decrease in the cytosolic NADP+-dependent isocitrate dehydrogenase activity through porcine sperm capacitation. 2018 Feb 26 3
10 29879375 IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity. 2018 Jun 7 4
11 28564604 Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. 2017 May 30 2
12 28827794 Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH). 2017 Aug 1
13 27049945 Reductive carboxylation supports redox homeostasis during anchorage-independent growth. 2016 Apr 14 2
14 27810736 Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration. 2016 Dec 2
15 25283382 Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation. 2015 Feb 3
16 26363012 Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198. 2015 Nov 15 2
17 24362902 An IDH1 mutation inhibits growth of glioma cells via GSH depletion and ROS generation. 2014 Jun 1
18 23115158 Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation. 2013 Jan 3
19 23541771 NADP+ -dependent IDH1 R132 mutation and its relevance for glioma patient survival. 2013 Jun 1
20 19291592 Glutathionylation regulates cytosolic NADP+-dependent isocitrate dehydrogenase activity. 2009 Apr 1