mucin 4, cell surface associated ; Homo sapiens






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1 1907285 Endocytosis of the ASGP receptor H1 is reduced by mutation of tyrosine-5 but still occurs via coated pits. J Cell Biol 1991 Aug 1
2 3478583 Mechanism of the phorbol ester-mediated redistribution of asialoglycoprotein receptor: selective effects on receptor recycling pathways in Hep G2 cells. Mol Pharmacol 1987 Sep 2
3 7745080 Mucin gene expression in the human endocervix. Hum Reprod 1995 Jan 1
4 7844558 The asialoglycoprotein receptor is a potential liver-specific receptor for Marburg virus. J Gen Virol 1995 Feb 1
5 8157358 Expression of MUC1, MUC2, MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines. Int J Cancer 1994 Apr 15 1
6 8554551 Mucin genes are regulated by estrogen and dexamethasone. Biochem Biophys Res Commun 1995 Dec 26 2
7 8573155 The human asialoglycoprotein receptor is palmitoylated and fatty deacylation causes inactivation of state 2 receptors. Biochem Biophys Res Commun 1996 Jan 5 3
8 9620877 Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat array. Biochem J 1998 Jun 15 1
9 9858486 MUC4 and MUC5B transcripts are the prevalent mucin messenger ribonucleic acids of the human endocervix. Biol Reprod 1999 Jan 2
10 10100990 Mucin gene expression during differentiation of human airway epithelia in vitro. Muc4 and muc5b are strongly induced. Am J Respir Cell Mol Biol 1999 Apr 1
11 10670468 Membrane-associated mucins in normal human conjunctiva. Invest Ophthalmol Vis Sci 2000 Feb 2
12 10844691 Gonococcal lipooligosaccharide is a ligand for the asialoglycoprotein receptor on human sperm. Mol Microbiol 2000 Jun 1
13 10920259 Human MUC4 mucin cDNA and its variants in pancreatic carcinoma. J Biochem 2000 Aug 4
14 10938282 Retinoic acid-dependent transforming growth factor-beta 2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-alpha signaling pathway. J Biol Chem 2000 Oct 27 5
15 11135323 Alternate splicing at the 3'-end of the human pancreatic tumor-associated mucin MUC4 cDNA. Teratog Carcinog Mutagen 2001 1
16 11192827 Two novel monoclonal antibodies against the MUC4 tandem repeat reacting with an antigen overexpressed by lung cancer. Int J Biol Markers 2000 Oct-Dec 2
17 12115478 Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance. Int J Cancer 2002 Jun 20 2
18 12171918 Nonpalmitoylated human asialoglycoprotein receptors recycle constitutively but are defective in coated pit-mediated endocytosis, dissociation, and delivery of ligand to lysosomes. J Biol Chem 2002 Oct 25 1
19 12359251 Palmitoylation-defective asialoglycoprotein receptors are normal in their cellular distribution and ability to bind ligand, but are defective in ligand uptake and degradation. Biochem Biophys Res Commun 2002 Oct 4 1
20 12386815 Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways. Oncogene 2002 Oct 24 1
21 12732353 Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells. Biochem Pharmacol 2003 May 1 4
22 12748185 Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells. J Biol Chem 2003 Aug 8 1
23 14583090 Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway. Biochem J 2004 Feb 1 12
24 14657954 Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma. Mod Pathol 2004 Feb 2
25 14691162 Differential regulation of membrane-associated mucins in the human ocular surface epithelium. Invest Ophthalmol Vis Sci 2004 Jan 2
26 14991920 Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines. Chem Rec 2004 1
27 15054739 MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma. Head Neck 2004 Apr 2
28 15284539 MUC4 and ErbB2 expression in squamous cell carcinoma of the upper aerodigestive tract: correlation with clinical outcomes. Laryngoscope 2004 Aug 2
29 15867264 Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia. Clin Cancer Res 2005 May 1 1
30 15998437 Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors. Liver Int 2005 Aug 3
31 16007204 Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene 2005 Sep 8 3
32 16201257 Feasibility on systemic delivery of asialoorosomucoid complex to hepatic origin cells mediated by asialoglycoprotein receptor. J Huazhong Univ Sci Technolog Med Sci 2005 2
33 16690615 The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3. J Biol Chem 2006 Jul 14 2
34 16779668 IL-9 modulated MUC4 gene and glycoprotein expression in airway epithelial cells. Biosci Rep 2006 Feb 2
35 17032197 MUC4-expressing pancreatic adenocarcinomas show elevated levels of both T1 and T2 cytokines: potential pathobiologic implications. Am J Gastroenterol 2006 Oct 2
36 17037983 Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. Biochem J 2007 Feb 15 6
37 17292332 Muc4 is required for activation of ErbB2 in signet ring carcinoma cell lines. Biochem Biophys Res Commun 2007 Mar 30 2
38 17425390 MUC4 expression in non-small cell lung carcinomas: relationship to tumor histology and patient survival. Arch Pathol Lab Med 2007 Apr 2
39 17525742 IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response. Oncogene 2007 Nov 8 1
40 17592322 Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone. Cornea 2007 Jul 3
41 17891050 Effect of glucocorticoid on the MUC4 gene in nasal polyps. Laryngoscope 2007 Dec 1
42 17972259 Copolymers for hepatocyte-specific targeting carrying galactose and hydrophobic alkyl groups. Macromol Biosci 2008 Mar 10 2
43 18008338 MUC4 is upregulated in ovarian carcinoma effusions and differentiates carcinoma cells from mesothelial cells. Diagn Cytopathol 2007 Dec 1
44 18024835 Structure, evolution, and biology of the MUC4 mucin. FASEB J 2008 Apr 1
45 18161881 Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. Hepatology 2008 May 1
46 18361519 Efficient synthesis of MUC4 sialylglycopeptide through the new sialylation using 5-acetamido-neuraminamide donors. J Org Chem 2008 May 2 3
47 18395283 Functionalized micelles from block copolymer of polyphosphoester and poly(epsilon-caprolactone) for receptor-mediated drug delivery. J Control Release 2008 May 22 4
48 18436821 Release of membrane-associated mucins from ocular surface epithelia. Invest Ophthalmol Vis Sci 2008 May 1
49 18492726 Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases. FASEB J 2008 Aug 5
50 18547287 Corticosteroid therapy increases membrane-tethered while decreases secreted mucin expression in nasal polyps. Allergy 2008 Oct 1