Protein Name mucin 4, cell surface associated
Organism Homo sapiens
Gene ID 4585
Gene Symbol

MUC4

UniProt Q99102 (MUC4_HUMAN), A0A0G2JS65 (A0A0G2JS65_HUMAN), A0T3F4 (A0T3F4_HUMAN), E9PDY6 (E9PDY6_HUMAN)
Relationships Total Number of functionally related compound(s) : 114
Total Number of Articles : 120
Description

mucin 4, cell surface associated

Gene Summary

The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]

synonyms
  • mucin-4
  • ascites sialoglycoprotein
  • mucin 4, tracheobronchial
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Properties