solute carrier family 3 member 2 ; Homo sapiens






171 Article(s)
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1 1376926 Stimulation of system y(+)-like amino acid transport by the heavy chain of human 4F2 surface antigen in Xenopus laevis oocytes. Proc Natl Acad Sci U S A 1992 Jun 15 26
2 1717576 Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux. J Immunol 1991 Oct 15 2
3 2789062 The 4F2 heavy chain gene: a molecular model of inducible gene expression in human T cells. J Autoimmun 1989 Jun 1
4 3036867 Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus. J Biol Chem 1987 Jul 15 1
5 3081629 B cell sensitivity to natural killing: correlation with target cell stage of differentiation and state of activation. J Immunol 1986 Mar 1 1
6 3265471 Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms. Mol Cell Biol 1988 Sep 6
7 3782435 Binding of monoclonal antibody (4F2) to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid hormone secretion. J Clin Endocrinol Metab 1987 Jan 5
8 6177771 Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines. J Immunol 1982 Aug 1
9 7920863 Poly(A)+ RNA from the mucosa of rat jejunum induces novel Na(+)-dependent and Na(+)-independent leucine transport activities in in oocytes of Xenopus laevis. Mol Membr Biol 1994 Apr-Jun 4
10 7927367 Preparation and characterization of a new monoclonal antibody CAF7 specific for a leukocyte activation antigen. Hybridoma 1994 Jun 1
11 8632680 Levels of CAF7 (CD98) expression correlate with the complete remission duration in childhood acute leukemia. Leuk Res 1996 Jan 1
12 8865806 Both the H13 gene product and 4F2 antigen are involved in the induction of system y+ cationic amino-acid transport following activation of human peripheral blood mononuclear cells (PBM). Biochim Biophys Acta 1996 Oct 2 1
13 9647208 Pentoxifylline inhibits adhesion and activation of human T lymphocytes. J Immunol 1998 Jul 1 1
14 9761775 The amino acid transport system y+L/4F2hc is a heteromultimeric complex. FASEB J 1998 Oct 7
15 9829974 Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance. J Biol Chem 1998 Dec 4 3
16 9878049 Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family. EMBO J 1999 Jan 4 1
17 10227815 Synergistic inhibition of human B cell activation by gold sodium thiomalate and auranofin. Clin Immunol 1999 May 1
18 10391915 Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids. J Biol Chem 1999 Jul 9 2
19 10506149 Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria. J Biol Chem 1999 Oct 8 1
20 10574970 LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine. J Biol Chem 1999 Dec 3 4
21 10631289 Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine. Biochim Biophys Acta 2000 Jan 15 2
22 10671548 Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains. J Biol Chem 2000 Feb 18 1
23 10734121 Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids. J Biol Chem 2000 Mar 31 2
24 10897033 Transformation of BALB3T3 cells caused by over-expression of rat CD98 heavy chain (HC) requires its association with light chain: mis-sense mutation in a cysteine residue of CD98HC eliminates its transforming activity. Int J Cancer 2000 Aug 1 4
25 10903140 The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. Biochem J 2000 Aug 1 5
26 10940652 Down-regulation of CD98 in melphalan-resistant myeloma cells with reduced drug uptake. Acta Haematol 2000 2
27 11069718 Induction of c-Src in human blood monocytes by anti-CD98/FRP-1 mAb in an Sp1-dependent fashion. Cell Immunol 2000 Sep 15 5
28 11133847 Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2001 Jan 2
29 11182559 3-[123I]iodo-alpha-methyl-L-tyrosine transport and 4F2 antigen expression in human glioma cells. Nucl Med Biol 2001 Jan 1
30 11213471 Molecular cloning and expression of human xCT, the light chain of amino acid transport system xc-. Antioxid Redox Signal 2000 Winter 3
31 11377971 The molecular bases of cystinuria and lysinuric protein intolerance. Curr Opin Genet Dev 2001 Jun 1
32 11389679 Role of the System L permease LAT1 in amino acid and iodothyronine transport in placenta. Biochem J 2001 Jun 15 2
33 11417227 Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-. Pflugers Arch 2001 May 4
34 11435306 The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation. Blood 2001 Jul 15 4
35 11461963 Dibutyryl-cAMP (dbcAMP) up-regulates astrocytic chloride-dependent L-[3H]glutamate transport and expression of both system xc(-) subunits. J Neurochem 2001 Jul 2
36 11546643 Function and structure of heterodimeric amino acid transporters. Am J Physiol Cell Physiol 2001 Oct 1
37 11557028 Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. Biochim Biophys Acta 2001 Oct 1 4
38 11564694 Thyroid hormone transport by the heterodimeric human system L amino acid transporter. Endocrinology 2001 Oct 10
39 11696247 Beta1 integrins show specific association with CD98 protein in low density membranes. BMC Biochem 2001 1
40 11766986 Heterodimeric amino acid transporters: molecular biology and pathological and pharmacological relevance. Curr Drug Metab 2001 Dec 2
41 12117417 Transport of a neurotoxicant by molecular mimicry: the methylmercury-L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2. Biochem J 2002 Oct 1 12
42 12270127 Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism. Biochem Biophys Res Commun 2002 Sep 27 1
43 12644836 Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines. Br J Cancer 2003 Mar 24 1
44 12729789 CD98-dependent homotypic aggregation is associated with translocation of protein kinase Cdelta and activation of mitogen-activated protein kinases. Exp Cell Res 2003 May 15 2
45 12737946 Early gene activation in chronic leukemic B lymphocytes induced toward a plasma cell phenotype. Blood Cells Mol Dis 2003 May-Jun 1
46 12740424 Manipulation of CD98 expression affects both trophoblast cell fusion and amino acid transport activity during syncytialization of human placental BeWo cells. J Physiol 2003 Jul 1 1
47 12839567 Rolipram inhibits polarization and migration of human T lymphocytes. J Invest Dermatol 2003 Jul 1
48 14668347 Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters. J Biol Chem 2004 Feb 27 1
49 14706635 Cynaropicrin, a sesquiterpene lactone, as a new strong regulator of CD29 and CD98 functions. Biochem Biophys Res Commun 2004 Jan 23 5
50 14743999 Continuous-wave and pulsed laser performance of Nd:LuVO4 crystal. Opt Lett 2004 Jan 15 1