Pub. Date : 2001 Oct 1
PMID : 11557028
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When expressed in Xenopus oocytes with human 4F2hc (h4F2hc), hLAT1 transports large neutral amino acids with high affinity (K(m)= approximately 15- approximately 50 microM) and L-glutamine and L-asparagine with low affinity (K(m)= approximately 1.5- approximately 2 mM). | Glutamine | solute carrier family 3 member 2 | Homo sapiens |
| 2 | When expressed in Xenopus oocytes with human 4F2hc (h4F2hc), hLAT1 transports large neutral amino acids with high affinity (K(m)= approximately 15- approximately 50 microM) and L-glutamine and L-asparagine with low affinity (K(m)= approximately 1.5- approximately 2 mM). | Asparagine | solute carrier family 3 member 2 | Homo sapiens |
| 3 | In Western blot analysis, hLAT1 and h4F2hc have been confirmed to be linked to each other via a disulfide bond in T24 human bladder carcinoma cells. | Disulfides | solute carrier family 3 member 2 | Homo sapiens |
| 4 | The properties of the hLAT1/h4F2hc complex would support the roles of this transporter in providing cells with essential amino acids for cell growth and cellular responses, and in distributing amino acid-related compounds. | Amino Acids, Essential | solute carrier family 3 member 2 | Homo sapiens |