NUAK family kinase 1 ; Homo sapiens






30 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 13679856 ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation. Oncogene 2003 Sep 18 3
2 14982852 ARK5 expression in colorectal cancer and its implications for tumor progression. Am J Pathol 2004 Mar 1
3 15273717 Regulation of caspase-6 and FLIP by the AMPK family member ARK5. Oncogene 2004 Sep 16 2
4 16014625 Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation. J Biol Chem 2005 Sep 9 3
5 18254724 Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains. Biochem J 2008 Apr 15 6
6 20354225 New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Sci Signal 2010 Mar 30 6
7 22433863 Inhibitory mechanism of caspase-6 phosphorylation revealed by crystal structures, molecular dynamics simulations, and biochemical assays. J Biol Chem 2012 May 4 1
8 22460906 Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature 2012 Mar 28 2
9 22483120 Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure 2012 Apr 4 1
10 22728884 Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines. Biochem Biophys Res Commun 2012 Jul 20 1
11 23063350 ARK5 promotes glioma cell invasion, and its elevated expression is correlated with poor clinical outcome. Eur J Cancer 2013 Feb 1
12 23215946 High NUAK1 expression correlates with poor prognosis and involved in NSCLC cells migration and invasion. Exp Lung Res 2013 Feb 2
13 24171924 Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J 2014 Jan 1 6
14 24785407 Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase. Biochem J 2014 Jul 15 4
15 27126361 ARK5 promotes doxorubicin resistance in hepatocellular carcinoma via epithelial-mesenchymal transition. Cancer Lett 2016 Jul 28 5
16 28469776 Inhibition of AMPK-related kinase 5 (ARK5) enhances cisplatin cytotoxicity in non-small cell lung cancer cells through regulation of epithelial-mesenchymal transition. Am J Transl Res 2017 5
17 28832761 Salinomycin enhances doxorubicin sensitivity through reversing the epithelial-mesenchymal transition of cholangiocarcinoma cells by regulating ARK5. Braz J Med Biol Res 2017 Aug 17 5
18 29100308 Integration of genomic, transcriptomic and functional profiles of aggressive osteosarcomas across multiple species. Oncotarget 2017 Sep 29 3
19 29106388 Calcium signalling links MYC to NUAK1. Oncogene 2018 Feb 22 3
20 29575772 LncRNA SNHG1 functions as a ceRNA to antagonize the effect of miR-145a-5p on the down-regulation of NUAK1 in nasopharyngeal carcinoma cell. J Cell Mol Med 2019 Apr 1
21 30121842 Expression level of NUAK1 in human nasopharyngeal carcinoma and its prognostic significance. Eur Arch Otorhinolaryngol 2018 Oct 1
22 30662653 AMPK-related kinase 5 (ARK5) enhances gemcitabine resistance in pancreatic carcinoma by inducing epithelial-mesenchymal transition. Am J Transl Res 2018 5
23 31949655 NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p. Int J Clin Exp Pathol 2018 2
24 31983282 DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy. Autophagy 2020 Oct 1
25 32754444 Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells. Front Oncol 2020 5
26 33310286 Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer. Eur J Med Chem 2021 Jan 15 2
27 33312374 WZ4003 sensitizes non-small cell lung cancer cells to gefitinib via inhibition of ARK5 and epithelial-to-mesenchymal transition. Am J Transl Res 2020 5
28 33372657 Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling. Elife 2020 Dec 29 1
29 33819186 Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin. Aging (Albany NY) 2021 Mar 26 4
30 34314378 Correction for: Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin. Aging (Albany NY) 2021 Jul 26 1