Title : Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells.

Pub. Date : 2020

PMID : 32754444






5 Functional Relationships(s)
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Protein Name
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1 Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells. Adenosine Triphosphate NUAK family kinase 1 Homo sapiens
2 Besides, NUAK1 supports cancer cell survival under metabolic stress and maintains ATP levels in hepatocarcinoma cells, suggesting a role in energy metabolism in cancer. Adenosine Triphosphate NUAK family kinase 1 Homo sapiens
3 We demonstrated that cytosolic NUAK1 increases ATP levels, which associates with increased mitochondrial respiration, supporting that cytosolic NUAK1 is involved in mitochondrial function regulation in cancer cells. Adenosine Triphosphate NUAK family kinase 1 Homo sapiens
4 We demonstrated that cytosolic NUAK1 increases ATP levels, which associates with increased mitochondrial respiration, supporting that cytosolic NUAK1 is involved in mitochondrial function regulation in cancer cells. Adenosine Triphosphate NUAK family kinase 1 Homo sapiens
5 Altogether, our results suggest that cytosolic NUAK1 participates in mitochondrial ATP production and the maintenance of proper glycolysis in cancer cells. Adenosine Triphosphate NUAK family kinase 1 Homo sapiens