Pub. Date : 2020
PMID : 32754444
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells. | Adenosine Triphosphate | NUAK family kinase 1 | Homo sapiens |
2 | Besides, NUAK1 supports cancer cell survival under metabolic stress and maintains ATP levels in hepatocarcinoma cells, suggesting a role in energy metabolism in cancer. | Adenosine Triphosphate | NUAK family kinase 1 | Homo sapiens |
3 | We demonstrated that cytosolic NUAK1 increases ATP levels, which associates with increased mitochondrial respiration, supporting that cytosolic NUAK1 is involved in mitochondrial function regulation in cancer cells. | Adenosine Triphosphate | NUAK family kinase 1 | Homo sapiens |
4 | We demonstrated that cytosolic NUAK1 increases ATP levels, which associates with increased mitochondrial respiration, supporting that cytosolic NUAK1 is involved in mitochondrial function regulation in cancer cells. | Adenosine Triphosphate | NUAK family kinase 1 | Homo sapiens |
5 | Altogether, our results suggest that cytosolic NUAK1 participates in mitochondrial ATP production and the maintenance of proper glycolysis in cancer cells. | Adenosine Triphosphate | NUAK family kinase 1 | Homo sapiens |