Title : Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines.

Pub. Date : 2012 Jul 20

PMID : 22728884






1 Functional Relationships(s)
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1 Whereas the earlier indeno[1,2-b]indoles have been shown to be selective for CK2, the indeno[1,2-b]indoloquinones 6b and 6c also inhibited the AMPK activated protein kinase ARK5, potentially contributing to the anti-cancer effects of the compounds. indeno(1,2-b)indoloquinone NUAK family kinase 1 Homo sapiens