angiopoietin-like 3 ; Mus musculus






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1 12097324 ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase. J Biol Chem 2002 Sep 13 4
2 12518032 Regulation of the angiopoietin-like protein 3 gene by LXR. J Lipid Res 2003 Jan 1
3 12565906 Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes. Biochem Biophys Res Commun 2003 Feb 7 2
4 12671033 A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice. J Lipid Res 2003 Jun 10
5 12909640 Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo. J Biol Chem 2003 Oct 24 2
6 15094378 ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states. Biochem Biophys Res Commun 2004 May 14 4
7 15336575 Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor. Biochem Biophys Res Commun 2004 Sep 24 8
8 16081640 Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology 2005 Nov 3
9 16508209 Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity. Exp Anim 2006 Jan 5
10 17110602 Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase. Arterioscler Thromb Vasc Biol 2007 Feb 9
11 18602396 Molecular characterization and expression of angiopoietin-like protein 3 in the chicken, Gallus gallus. Gen Comp Endocrinol 2008 Aug 4
12 19067122 Effects of high dietary fat and cholesterol on expression of PPAR alpha, LXR alpha, and their responsive genes in the liver of apoE and LDLR double deficient mice. Mol Cell Biochem 2009 Mar 1
13 19088802 Beneficial effect of 3,4,5,6-tetrahydroxyxanthone on dyslipidemia in apolipoprotein E-deficient mice. Can J Physiol Pharmacol 2008 Dec 3
14 19318355 Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL). J Biol Chem 2009 May 15 6
15 19540497 Plasma angiopoietin-like protein 3 (ANGPTL3) concentration is associated with uremic dyslipidemia. Atherosclerosis 2009 Dec 3
16 19542565 GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4. J Lipid Res 2009 Dec 1
17 22063269 Regulation of triglyceride metabolism by Angiopoietin-like proteins. Biochim Biophys Acta 2012 May 1
18 22342712 1,3,5,8-tetrahydroxyxanthone regulates ANGPTL3-LPL pathway to lessen the ketosis in mice. Eur J Pharm Sci 2012 May 12 1
19 23150577 Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A 2012 Nov 27 3
20 25710887 A novel role of angiopoietin-like-3 associated with podocyte injury. Pediatr Res 2015 Jun 1
21 25884163 A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro. BMC Nephrol 2015 Mar 29 1
22 25954050 Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion. J Lipid Res 2015 Jul 4
23 25964512 ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys. J Lipid Res 2015 Jul 2
24 26305978 Hepatic ANGPTL3 regulates adipose tissue energy homeostasis. Proc Natl Acad Sci U S A 2015 Sep 15 2
25 28413163 ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance. J Lipid Res 2017 Jun 3
26 28538111 Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides. N Engl J Med 2017 Jul 20 3
27 28984319 Angiopoietin-like 3 in lipoprotein metabolism. Nat Rev Endocrinol 2017 Dec 2
28 29031715 ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase. Mol Metab 2017 Oct 3
29 29183623 Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis 2018 Jan 3
30 29334984 New insights into ANGPLT3 in controlling lipoprotein metabolism and risk of cardiovascular diseases. Lipids Health Dis 2018 Jan 15 1
31 29752428 Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia. J Biomed Res 2019 Apr 22 2
32 30096295 Paeoniflorin regulates GALNT2-ANGPTL3-LPL pathway to attenuate dyslipidemia in mice. Eur J Pharmacol 2018 Oct 5 3
33 30944669 Effects of Angiopoietin-Like 3 on Triglyceride Regulation, Glucose Homeostasis, and Diabetes. Dis Markers 2019 7
34 31126248 Angiopoietin-like-3 knockout protects against glomerulosclerosis in murine adriamycin-induced nephropathy by attenuating podocyte loss. BMC Nephrol 2019 May 24 3
35 31256934 Anti-proteinuria effect of antibody against ANGPTL3 coil-coiled domain on adriamycin-induced nephropathy in mice. Biochem Biophys Res Commun 2019 Aug 27 2
36 32808882 LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase. Circ Res 2020 Sep 25 1
37 33649229 Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of <i>Angptl3</i>. Proc Natl Acad Sci U S A 2021 Mar 9 1
38 34298929 Angiopoietin-Like Protein 3 (ANGPTL3) Modulates Lipoprotein Metabolism and Dyslipidemia. Int J Mol Sci 2021 Jul 7 1
39 34371033 Antisense oligonucleotide-mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice. J Lipid Res 2021 5
40 34474934 A VLP-based vaccine targeting ANGPTL3 lowers plasma triglycerides in mice. Vaccine 2021 Sep 24 9
41 34499887 PPARα agonist exerts protective effects in podocyte injury via inhibition of the ANGPTL3 pathway. Exp Cell Res 2021 Oct 15 2
42 34841293 Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia. Cell Rep Med 2021 Nov 16 2
43 34951653 Impact of oral lipid and glucose tolerance tests on the postprandial concentrations of angiopoietin-like proteins (Angptl) 3 and 4. Eur J Nutr 2022 Jun 4
44 35086056 Podocyte protection by Angptl3 knockout via inhibiting ROS/GRP78 pathway in LPS-induced acute kidney injury. Int Immunopharmacol 2022 Apr 5
45 35171673 Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia. Sci Adv 2022 Feb 18 2
46 35454174 The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway. Biomolecules 2022 Apr 16 4