Pub. Date : 2021 Oct 15
PMID : 34499887
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PPARalpha mRNA and protein levels decreased whereas ANGPTL3 mRNA and protein levels increased in a time-dependent manner in podocytes treated with puromycin aminonucleoside (PAN). | Puromycin Aminonucleoside | angiopoietin-like 3 | Mus musculus |
| 2 | This study identified a novel mechanism of the PPARalpha agonist gemfibrozil that exerts its protective effects by inhibiting PAN-induced apoptosis and cytoskeleton rearrangements through inhibition of ANGPTL3 expression. | Gemfibrozil | angiopoietin-like 3 | Mus musculus |