coagulation factor II (thrombin) receptor ; Mus musculus






129 Article(s)
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1 9097912 Calorie restriction decreases platelet-derived growth factor (PDGF)-A and thrombin receptor mRNA expression in autoimmune murine lupus nephritis. Clin Exp Immunol 1997 Apr 1
2 9125155 Hypotonicity and thrombin activate taurine efflux in BC3H1 and C2C12 myoblasts that is down regulated during differentiation. Biochem Biophys Res Commun 1997 Mar 6 1
3 9564545 Receptor-activating peptides distinguish thrombin receptor (PAR-1) and protease activated receptor 2 (PAR-2) mediated hemodynamic responses in vivo. Can J Physiol Pharmacol 1998 Jan 1
4 10029617 Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle. Gastroenterology 1999 Mar 2
5 10694203 Modulation of airway smooth muscle tone by protease activated receptor-1,-2,-3 and -4 in trachea isolated from influenza A virus-infected mice. Br J Pharmacol 2000 Jan 2
6 11030717 Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br J Pharmacol 2000 Oct 2
7 11120874 Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice. Physiol Genomics 2000 Dec 18 1
8 11156565 Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea. Br J Pharmacol 2001 Jan 2
9 11413145 Thrombin receptor signaling to cytoskeleton requires Hsp90. J Biol Chem 2001 Aug 31 1
10 11850418 Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. J Biol Chem 2002 May 3 2
11 11855866 Dissection of protease-activated receptor-1-dependent and -independent responses to thrombin in skeletal myoblasts. Exp Cell Res 2002 Mar 10 1
12 12114324 Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circ Res 2002 Jul 12 1
13 12370392 Thrombin induces mast cell adhesion to fibronectin: evidence for involvement of protease-activated receptor-1. J Immunol 2002 Oct 15 3
14 12594292 Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis. J Immunol 2003 Mar 1 1
15 12717003 Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J Physiol 2003 Jun 15 6
16 12900053 Identification, purification and characterization of a receptor for dengue virus-induced macrophage cytotoxin (CF2) from murine T cells. FEMS Immunol Med Microbiol 2003 Aug 18 2
17 14608379 Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure. Nat Med 2003 Dec 3
18 14633513 Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice. Am J Physiol Lung Cell Mol Physiol 2004 Feb 2
19 15086339 Trypsin induces epidermal proliferation and inflammation in murine skin. Exp Dermatol 2004 Apr 2
20 15210836 The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1. J Pharmacol Exp Ther 2004 Nov 3
21 15345469 Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am J Physiol Gastrointest Liver Physiol 2005 Feb 2
22 15381162 Studies on the receptors mediating responses of osteoblasts to thrombin. Int J Biochem Cell Biol 2005 Jan 2
23 15545995 A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest 2004 Nov 3
24 15681708 Protease-activated receptor and endothelial-myocyte uncoupling in chronic heart failure. Am J Physiol Heart Circ Physiol 2005 Jun 3
25 15723127 Effect of synthetic peptide thrombin receptor agonist encapsulated in microparticles based on lactic and glycolic acid copolymer on healing of experimental skin wounds in mice. Bull Exp Biol Med 2004 Nov 7
26 15855637 Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis. Am J Pathol 2005 May 4
27 15907810 Two types of protease-activated receptors (PAR-1 and PAR-2) mediate calcium signaling in rat retinal ganglion cells RGC-5. Brain Res 2005 Jun 21 2
28 16116312 Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response. Inflamm Bowel Dis 2005 Sep 4
29 16188279 Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro. Life Sci 2006 Jan 25 2
30 16251448 Protease-activated receptor-1 and platelet-derived growth factor in spinal cord neurons are implicated in neuropathic pain after nerve injury. J Neurosci 2005 Oct 26 1
31 16710477 Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest 2006 Jun 1
32 17122062 The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. J Neurosci 2006 Nov 22 10
33 17188433 Radiation-induced production of PAR-1 and TGF-beta 1 mRNA in lung of C57Bl6 and C3H murine strains and influence of pharmacoprophylaxis by ACE inhibitors. Pathol Res Pract 2007 1
34 17267741 Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals. J Am Soc Nephrol 2007 Mar 1
35 17286591 Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system. J Neurochem 2007 Jun 11
36 17431214 Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder. Am J Physiol Gastrointest Liver Physiol 2007 Jul 2
37 17577318 Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. Basic Clin Pharmacol Toxicol 2007 Jul 3
38 17596374 Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1. Mol Pharmacol 2007 Sep 7
39 17654741 Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice. Hepatology 2007 Oct 1
40 18398001 Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells. J Cell Sci 2008 May 1 2
41 18411702 [Regulation by tissue plasminogen activator of rewarding effects of drugs of abuse]. Nihon Shinkei Seishin Yakurigaku Zasshi 2008 Feb 4
42 18646640 [Role of tissue plasminogen activator in the rewarding effect of nicotine]. Nihon Arukoru Yakubutsu Igakkai Zasshi 2008 Jun 5
43 18974154 Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA. Cancer Res 2008 Nov 1 2
44 18987429 Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice. J Pharmacol Sci 2008 Nov 2
45 19012179 Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets. Platelets 2008 Dec 3
46 19060230 Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med 2009 Mar 1 1
47 19098386 Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1. J Pharmacol Sci 2008 Dec 7
48 19416668 Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function. Exp Neurol 2009 May 4
49 19674841 Thrombin receptor: An endogenous inhibitor of inflammatory pain, activating opioid pathways. Pain 2009 Nov 4
50 19706295 Protease-activated receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori. Gastroenterology 2010 Feb 1