| Protein Name | coagulation factor II thrombin receptor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14062 |
| Gene Symbol | F2r |
| UniProt | P30558 (PAR1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
120
Total Number of Articles : 129 |
Description |
coagulation factor II thrombin receptor |
| Gene Summary |
Enables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of renin secretion into blood stream; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including dendritic cell homeostasis; regulation of interleukin-1 beta production; and thrombin-activated receptor signaling pathway. Predicted to be located in several cellular components, including endosome; platelet dense tubular network; and postsynaptic membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and lung. Orthologous to human F2R (coagulation factor II thrombin receptor). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |