| 1 | 12718900 | Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease. | Mol Ther | 2003 May |
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| 2 | 15246864 | Aspartoacylase deficiency does not affect N-acetylaspartylglutamate level or glutamate carboxypeptidase II activity in the knockout mouse brain. | Brain Res | 2004 Aug 6 |
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| 3 | 15784740 | Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease. | Proc Natl Acad Sci U S A | 2005 Apr 5 |
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| 4 | 16707098 | Upregulation of aspartoacylase activity in the duodenum of obesity induced diabetes mouse: implications on diabetic neuropathy. | Biochem Biophys Res Commun | 2006 Jul 7 |
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| 5 | 17460362 | Absence-like and tonic seizures in aspartoacylase/attractin double-mutant mice. | Exp Anim | 2007 Apr |
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| 6 | 18987190 | Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS. | J Neurosci | 2008 Nov 5 |
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| 7 | 21625469 | Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease. | PLoS One | 2011 |
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| 8 | 24272958 | Astroglial redistribution of aquaporin 4 during spongy degeneration in a Canavan disease mouse model. | J Mol Neurosci | 2014 May |
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| 9 | 24288037 | Dietary triheptanoin rescues oligodendrocyte loss, dysmyelination and motor function in the nur7 mouse model of Canavan disease. | J Inherit Metab Dis | 2014 May |
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| 10 | 24682784 | A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination. | Dis Model Mech | 2014 Jun |
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| 11 | 24826990 | Loss of central auditory processing in a mouse model of Canavan disease. | PLoS One | 2014 |
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| 12 | 25024137 | Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. | J Exp Med | 2014 Jul 28 |
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| 13 | 25712859 | Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model. | Ann Neurol | 2015 May |
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| 14 | 25766789 | Transcriptional regulation of N-acetylaspartate metabolism in the 5xFAD model of Alzheimer's disease: evidence for neuron-glia communication during energetic crisis. | Mol Cell Neurosci | 2015 Mar |
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| 15 | 26511242 | N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time. | J Neurosci | 2015 Oct 28 |
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| 16 | 27709268 | The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition. | Exp Brain Res | 2017 Jan |
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| 17 | 28077719 | Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy. | J Neurosci | 2017 Jan 11 |
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| 18 | 28194442 | Redirecting <i>N</i>-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease. | JCI Insight | 2017 Feb 9 |
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| 19 | 28626388 | Increasing N-acetylaspartate in the Brain during Postnatal Myelination Does Not Cause the CNS Pathologies of Canavan Disease. | Front Mol Neurosci | 2017 |
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| 20 | 29456021 | Brain Nat8l Knockdown Suppresses Spongiform Leukodystrophy in an Aspartoacylase-Deficient Canavan Disease Mouse Model. | Mol Ther | 2018 Mar 7 |
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| 21 | 31958766 | GC-MS based metabolomic profiling of lung tissue couple with network pharmacology revealed the possible protection mechanism of Pudilan Xiaoyan Oral Liquid in LPS-induced lung injury of mice. | Biomed Pharmacother | 2020 Apr |
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| 22 | 34498299 | Ablating the Transporter Sodium-Dependent Dicarboxylate Transporter 3 Prevents Leukodystrophy in Canavan Disease Mice. | Ann Neurol | 2021 Nov |
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