| 1 | 16936195 | Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. | Diabetes | 2006 Sep |
1 |
| 2 | 19435858 | Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways. | Am J Physiol Endocrinol Metab | 2009 Jul |
1 |
| 3 | 19660458 | Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes. | FEBS Lett | 2009 Sep 3 |
4 |
| 4 | 19706786 | Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects. | Am J Physiol Endocrinol Metab | 2009 Nov |
2 |
| 5 | 20163718 | High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli. | BMC Biotechnol | 2010 Feb 17 |
4 |
| 6 | 20357365 | Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats. | Diabetes | 2010 Jul |
3 |
| 7 | 21317437 | Thermogenic activation induces FGF21 expression and release in brown adipose tissue. | J Biol Chem | 2011 Apr 15 |
5 |
| 8 | 22891896 | Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction. | Appl Physiol Nutr Metab | 2012 Dec |
7 |
| 9 | 23118742 | Metformin stimulates FGF21 expression in primary hepatocytes. | Exp Diabetes Res | 2012 |
2 |
| 10 | 23123503 | Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. | Biochimie | 2013 Apr |
1 |
| 11 | 23305840 | FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Cι/λ. | Eur J Pharmacol | 2013 Feb 28 |
6 |
| 12 | 24041694 | Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation. | Biochem Biophys Res Commun | 2013 Oct 11 |
1 |
| 13 | 24117266 | Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia-reperfusion injury. | Can J Physiol Pharmacol | 2013 Nov |
4 |
| 14 | 24159189 | Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. | Dis Model Mech | 2014 Jan |
1 |
| 15 | 24358774 | [Therapeutic effect of fibroblast growth factor 21 on hypertension induced by insulin resistance]. | Yao Xue Xue Bao | 2013 Sep |
4 |
| 16 | 24468826 | FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers. | Mol Psychiatry | 2015 Feb |
10 |
| 17 | 24733293 | Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism. | PLoS One | 2014 |
11 |
| 18 | 24974463 | [FGF-21 protects H9c2 cardiomyoblasts against hydrogen peroxide-induced oxidative stress injury]. | Yao Xue Xue Bao | 2014 Apr |
5 |
| 19 | 25119860 | Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hormones of energy balance in a TCDD-sensitive and a TCDD-resistant rat strain. | Int J Mol Sci | 2014 Aug 12 |
2 |
| 20 | 25306889 | Recombinant murine fibroblast growth factor 21 ameliorates obesity-related inflammation in monosodium glutamate-induced obesity rats. | Endocrine | 2015 May |
6 |
| 21 | 25313624 | Effects of fibroblast growth factor 21 on cell damage in vitro and atherosclerosis in vivo. | Can J Physiol Pharmacol | 2014 Nov |
10 |
| 22 | 25920593 | Betaine alleviates hepatic lipid accumulation via enhancing hepatic lipid export and fatty acid oxidation in rats fed with a high-fat diet. | Br J Nutr | 2015 Jun 28 |
2 |
| 23 | 26153793 | FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance. | Sci Rep | 2015 Jul 8 |
2 |
| 24 | 26266088 | Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response. | Mol Metab | 2015 Aug |
1 |
| 25 | 26323321 | Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1α/PPARα-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth. | Mol Med Rep | 2015 Nov |
1 |
| 26 | 26634512 | MiR-577 inhibits pancreatic β-cell function and survival by targeting fibroblast growth factor 21 (FGF-21) in pediatric diabetes. | Genet Mol Res | 2015 Dec 1 |
5 |
| 27 | 26652990 | [Effects and mechanism of fibroblast growth factor 21 on rat vascular smooth muscle cells calcification]. | Zhonghua Xin Xue Guan Bing Za Zhi | 2015 Oct |
1 |
| 28 | 27133430 | Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague-Dawley rats fed prenatal low protein and postnatal high-fat diets. | J Nutr Biochem | 2016 May |
1 |
| 29 | 27187182 | A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis. | PLoS One | 2016 |
1 |
| 30 | 27248050 | Upregulation of rat liver PPARα-FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol. | Biofactors | 2016 Nov 12 |
5 |
| 31 | 27387420 | FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats. | Sci Rep | 2016 Jul 8 |
1 |
| 32 | 27445299 | Fibroblast growth factor 21 is required for beneficial effects of exercise during chronic high-fat feeding. | J Appl Physiol (1985) | 2016 Sep 1 |
2 |
| 33 | 27875248 | Vildagliptin and caloric restriction for cardioprotection in pre-diabetic rats. | J Endocrinol | 2017 Feb |
1 |
| 34 | 27998432 | [Study on the kidney impairment and expressions of FGF21 from a rat model of vascular calcification]. | Zhonghua Yi Xue Za Zhi | 2016 Dec 13 |
3 |
| 35 | 28337713 | The Potential Role of Fibroblast Growth Factor 21 in Lipid Metabolism and Hypertension. | Curr Hypertens Rep | 2017 Apr |
2 |
| 36 | 28413172 | The effects of metformin on fibroblast growth factor 19, 21 and fibroblast growth factor receptor 1 in high-fat diet and streptozotocin induced diabetic rats. | Endocr J | 2017 May 30 |
2 |
| 37 | 28559436 | Hepatic FGF21 mediates sex differences in high-fat high-fructose diet-induced fatty liver. | Am J Physiol Endocrinol Metab | 2017 Aug 1 |
1 |
| 38 | 28774557 | Fibroblast growth factor 21 plays an inhibitory role in vascular calcification in vitro through OPG/RANKL system. | Biochem Biophys Res Commun | 2017 Sep 23 |
2 |
| 39 | 28890831 | Effects of central fibroblast growth factor 21 and irisin in anxiety-like behavior. | J Biol Regul Homeost Agents | 2017 Jul-Sep |
2 |
| 40 | 28942443 | A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats. | Cell Physiol Biochem | 2017 |
3 |
| 41 | 28949374 | Fibroblast growth factor 21 protects rat cardiomyocytes from endoplasmic reticulum stress by promoting the fibroblast growth factor receptor 1-extracellular signal‑regulated kinase 1/2 signaling pathway. | Int J Mol Med | 2017 Nov |
2 |
| 42 | 28990606 | A combined docosahexaenoic acid-thyroid hormone protocol upregulates rat liver β-Klotho expression and downstream components of FGF21 signaling as a potential novel approach to metabolic stress conditions. | Food Funct | 2017 Nov 15 |
14 |
| 43 | 29036766 | Resistance training increases fibroblast growth factor-21 and irisin levels in the skeletal muscle of Zucker diabetic fatty rats. | J Exerc Nutrition Biochem | 2017 Sep 30 |
1 |
| 44 | 29257234 | Therapeutic effects of fibroblast growth factor‑21 against atherosclerosis via the NF‑κB pathway. | Mol Med Rep | 2018 Jan |
3 |
| 45 | 29273504 | Fibroblast growth factor 21 ameliorates vascular calcification by inhibiting osteogenic transition in vitamin D3 plus nicotine-treated rats. | Biochem Biophys Res Commun | 2018 Jan 22 |
4 |
| 46 | 29311680 | Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy. | Sci Rep | 2018 Jan 8 |
1 |
| 47 | 29483386 | Protection Effect of Exogenous Fibroblast Growth Factor 21 on the Kidney Injury in Vascular Calcification Rats. | Chin Med J (Engl) | 2018 Mar 5 |
1 |
| 48 | 30009570 | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | Physiol Rep | 2018 Jul |
1 |
| 49 | 30106981 | FGF21 increases water intake, urine output and blood pressure in rats. | PLoS One | 2018 |
6 |
| 50 | 30197006 | Fibroblast growth factor 21 attenuates hypoxia-induced pulmonary hypertension by upregulating PPARγ expression and suppressing inflammatory cytokine levels. | Biochem Biophys Res Commun | 2018 Oct 2 |
3 |