Pub. Date : 2014 Nov
PMID : 25313624
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fibroblast growth factor 21 (FGF-21), which is a modulator of glucose and lipid homeostasis, acts as a novel therapeutic reagent for many metabolic perturbations. | Glucose | fibroblast growth factor 21 | Rattus norvegicus |
| 2 | Fibroblast growth factor 21 (FGF-21), which is a modulator of glucose and lipid homeostasis, acts as a novel therapeutic reagent for many metabolic perturbations. | Glucose | fibroblast growth factor 21 | Rattus norvegicus |
| 3 | The results indicated that FGF-21 significantly enhanced cell viability and decreased the degree of DNA fragmentation in HUVECs, as caused by H2O2 stress induction. | Hydrogen Peroxide | fibroblast growth factor 21 | Rattus norvegicus |
| 4 | Further studies revealed that FGF-21 inhibited H2O2-induced cell apoptosis by preventing the activation of mitogen-activated protein kinase (MAPK) signaling pathways. | Hydrogen Peroxide | fibroblast growth factor 21 | Rattus norvegicus |
| 5 | In an established rat model, FGF-21 dramatically improved the condition of atherosclerotic rats by decreasing serum levels of total triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and total cholesterol (TC), and by increasing the serum levels of high density lipoprotein cholesterol (HDL-C). | Triglycerides | fibroblast growth factor 21 | Rattus norvegicus |
| 6 | In an established rat model, FGF-21 dramatically improved the condition of atherosclerotic rats by decreasing serum levels of total triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and total cholesterol (TC), and by increasing the serum levels of high density lipoprotein cholesterol (HDL-C). | Triglycerides | fibroblast growth factor 21 | Rattus norvegicus |
| 7 | In an established rat model, FGF-21 dramatically improved the condition of atherosclerotic rats by decreasing serum levels of total triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and total cholesterol (TC), and by increasing the serum levels of high density lipoprotein cholesterol (HDL-C). | Cholesterol | fibroblast growth factor 21 | Rattus norvegicus |
| 8 | In an established rat model, FGF-21 dramatically improved the condition of atherosclerotic rats by decreasing serum levels of total triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and total cholesterol (TC), and by increasing the serum levels of high density lipoprotein cholesterol (HDL-C). | Technetium | fibroblast growth factor 21 | Rattus norvegicus |
| 9 | FGF-21 also has antioxidant effects in the atherosclerotic rat, such that increased levels of superoxide dismutase, reduced glutathione, and reduced malondialdehyde were observed. | Glutathione | fibroblast growth factor 21 | Rattus norvegicus |
| 10 | FGF-21 also has antioxidant effects in the atherosclerotic rat, such that increased levels of superoxide dismutase, reduced glutathione, and reduced malondialdehyde were observed. | Malondialdehyde | fibroblast growth factor 21 | Rattus norvegicus |