| 1 | 9079627 | TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. | J Biol Chem | 1997 Mar 28 |
5 |
| 2 | 9674701 | Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. | Oncogene | 1998 Jul 16 |
2 |
| 3 | 10607714 | HLA class I-restricted lysis of leukemia cells by a CD8(+) cytotoxic T-lymphocyte clone specific for WT1 peptide. | Blood | 2000 Jan 1 |
2 |
| 4 | 10702308 | TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop. | J Biol Chem | 2000 Mar 10 |
5 |
| 5 | 10838074 | Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1. | FEBS Lett | 2000 Jun 2 |
2 |
| 6 | 10882101 | TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. | Mol Cell | 2000 Apr |
2 |
| 7 | 11397816 | Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1. | J Biol Chem | 2001 Aug 10 |
2 |
| 8 | 11438700 | Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells. | Proc Natl Acad Sci U S A | 2001 Jul 17 |
3 |
| 9 | 11699391 | Immunotherapy for leukemia targeting the Wilms' tumor gene. | Leuk Lymphoma | 2001 Jul |
1 |
| 10 | 12609980 | Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR . | J Biol Chem | 2003 May 9 |
3 |
| 11 | 12624112 | A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase. | J Biol Chem | 2003 May 16 |
7 |
| 12 | 14670075 | TAB3, a new binding partner of the protein kinase TAK1. | Biochem J | 2004 Feb 15 |
4 |
| 13 | 14982987 | Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. | Proc Natl Acad Sci U S A | 2004 Mar 9 |
1 |
| 14 | 15075345 | Reciprocal cross-talk between Nod2 and TAK1 signaling pathways. | J Biol Chem | 2004 Jun 11 |
1 |
| 15 | 15327770 | TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. | Mol Cell | 2004 Aug 27 |
1 |
| 16 | 15492226 | TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6. | Proc Natl Acad Sci U S A | 2004 Oct 26 |
3 |
| 17 | 15590691 | Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. | J Biol Chem | 2005 Feb 25 |
17 |
| 18 | 15764709 | STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation. | Proc Natl Acad Sci U S A | 2005 Mar 22 |
3 |
| 19 | 16000313 | 15S-Lipoxygenase-2 mediates arachidonic acid-stimulated adhesion of human breast carcinoma cells through the activation of TAK1, MKK6, and p38 MAPK. | J Biol Chem | 2005 Sep 9 |
2 |
| 20 | 16050801 | Silica induces human cyclooxygenase-2 gene expression through the NF-kappaB signaling pathway. | J Environ Pathol Toxicol Oncol | 2005 |
2 |
| 21 | 16251197 | TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd. | Hum Mol Genet | 2005 Dec 1 |
2 |
| 22 | 16293250 | TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells. | FEBS Lett | 2005 Dec 5 |
4 |
| 23 | 16498455 | Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL. | Cell Death Differ | 2006 Nov |
1 |
| 24 | 16537514 | Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides. | Proc Natl Acad Sci U S A | 2006 Mar 14 |
1 |
| 25 | 16785236 | Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. | J Biol Chem | 2006 Aug 18 |
1 |
| 26 | 16835226 | Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. | J Biol Chem | 2006 Sep 1 |
1 |
| 27 | 17079228 | Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway. | J Biol Chem | 2006 Dec 29 |
7 |
| 28 | 17114179 | Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. | J Biol Chem | 2007 Jan 5 |
2 |
| 29 | 17172402 | Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade. | Mol Cancer Ther | 2006 Dec |
1 |
| 30 | 17172471 | Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages. | J Biol Chem | 2007 Feb 23 |
9 |
| 31 | 17277159 | Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kappaB-dependent antiapoptotic gene products: role of IkappaBalpha kinase and TGF-beta-activated kinase-1. | J Immunol | 2007 Feb 15 |
2 |
| 32 | 17332240 | Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. | Blood | 2007 Jun 15 |
2 |
| 33 | 17348859 | Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. | Biochem J | 2007 Jun 1 |
5 |
| 34 | 17387141 | Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation. | Mol Pharmacol | 2007 Jun |
2 |
| 35 | 17418100 | HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination. | Biochem Biophys Res Commun | 2007 May 25 |
1 |
| 36 | 17439942 | Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue. | J Biol Chem | 2007 Jun 15 |
1 |
| 37 | 17496917 | Ubiquitin-mediated activation of TAK1 and IKK. | Oncogene | 2007 May 14 |
2 |
| 38 | 18021073 | Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex. | Biochem J | 2008 Feb 1 |
4 |
| 39 | 18293403 | Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury. | Glia | 2008 May |
2 |
| 40 | 18299321 | Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cells. | J Biol Chem | 2008 Apr 18 |
6 |
| 41 | 18326498 | Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation. | J Biol Chem | 2008 May 23 |
2 |
| 42 | 18456659 | TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB. | J Biol Chem | 2008 Jul 11 |
1 |
| 43 | 18566231 | Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. | Mol Cancer Ther | 2008 Jun |
2 |
| 44 | 18599178 | Toxicological analysis of low-nicotine and nicotine-free cigarettes. | Toxicology | 2008 Jul 30 |
2 |
| 45 | 18603781 | Epoxyquinol B, a naturally occurring pentaketide dimer, inhibits NF-kappaB signaling by crosslinking TAK1. | Biosci Biotechnol Biochem | 2008 Jul |
3 |
| 46 | 18758450 | The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. | Nat Cell Biol | 2008 Oct |
4 |
| 47 | 18762249 | Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling. | Cell Signal | 2008 Nov |
11 |
| 48 | 18818394 | CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. | Blood | 2008 Dec 15 |
1 |
| 49 | 18950863 | Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling. | Mol Immunol | 2009 Feb |
2 |
| 50 | 19049961 | Tubocapsanolide A inhibits transforming growth factor-beta-activating kinase 1 to suppress NF-kappaB-induced CCR7. | J Biol Chem | 2009 Jan 30 |
1 |