sodium voltage-gated channel alpha subunit 9 ; Homo sapiens






265 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
51 23760503 Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin huwentoxin-IV (μ-TRTX-Hh2a). J Biol Chem 2013 Aug 2 3
52 23818614 Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels. Proc Natl Acad Sci U S A 2013 Jul 16 2
53 23836888 CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking. J Biol Chem 2013 Aug 23 1
54 23874707 Linkage between increased nociception and olfaction via a SCN9A haplotype. PLoS One 2013 1
55 23986482 Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells. J Cell Sci 2013 Nov 1 2
56 24082113 Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models. Proc Natl Acad Sci U S A 2013 Oct 22 2
57 24154831 Ion channel recordings on an injection-molded polymer chip. Lab Chip 2013 Dec 21 1
58 24192167 Structural and docking studies of potent ethionamide boosters. Acta Crystallogr C 2013 Nov 1
59 24272479 Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough. Lung 2014 Feb 1
60 24401712 Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H. J Neurophysiol 2014 Apr 1
61 24486399 Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate. Eur J Pharmacol 2014 Mar 15 2
62 24534904 Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. Anesthesiology 2014 Jun 2
63 24566628 An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition. Infect Immun 2014 May 3
64 24840382 Upregulation of nav1.7 through high salt loading: (mol pain 2013;9:39). J Neurogastroenterol Motil 2014 Apr 30 1
65 24866741 Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels. Br J Pharmacol 2014 Oct 4
66 25026046 Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels. J Med Chem 2014 Aug 14 1
67 25029427 Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis. J Clin Endocrinol Metab 2014 Sep 1
68 25176194 The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7. Bioorg Med Chem Lett 2014 Sep 15 1
69 25218973 Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels. Peptides 2015 Jun 1
70 25221944 Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain. PLoS One 2014 2
71 25240195 Protein kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III-IV linker. FEBS Lett 2014 Nov 3 1
72 25466191 Dibenzazepines and dibenzoxazepines as sodium channel blockers. Bioorg Med Chem Lett 2015 Jan 1 1
73 25658507 Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel. J Med Chem 2015 Mar 12 3
74 26068619 Comparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine. PLoS One 2015 8
75 26187311 Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs. Eur J Pharmacol 2015 Oct 5 5
76 26220736 Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. Br J Pharmacol 2015 Oct 1
77 26225903 Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. ACS Chem Neurosci 2015 Oct 21 1
78 26351759 Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? Pulm Pharmacol Ther 2015 Dec 1
79 26429937 Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7. Mol Pharmacol 2015 Dec 2
80 26581770 The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. Sci Rep 2015 Nov 19 1
81 26586647 A review of the use of ethionamide and prothionamide in childhood tuberculosis. Tuberculosis (Edinb) 2016 Mar 6
82 26634308 Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7. Nat Commun 2015 Dec 4 1
83 26859646 Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity. Anesthesiology 2016 May 1
84 26890998 Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx-1. J Med Chem 2016 Mar 24 2
85 26891306 Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin. Mar Drugs 2016 Feb 16 8
86 26991361 Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening. Assay Drug Dev Technol 2016 Mar 1
87 27033404 Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. Fitoterapia 2016 Jun 1
88 27050761 Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. PLoS One 2016 2
89 27088781 Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. JAMA Neurol 2016 Jun 1 2
90 27162340 Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7. Proc Natl Acad Sci U S A 2016 May 24 2
91 27215841 Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels. Elife 2016 May 24 1
92 27291053 Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. Curr Biol 2016 Jun 20 2
93 27363506 Efficacy, safety, and tolerability of lacosamide in patients with gain-of-function Nav1.7 mutation-related small fiber neuropathy: study protocol of a randomized controlled trial-the LENSS study. Trials 2016 Jun 30 5
94 27402262 [Pain and analgesia : Mutations of voltage-gated sodium channels]. Schmerz 2017 Feb 1
95 27587537 The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels. Mol Pharmacol 2016 Nov 3
96 27598514 SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing. PLoS One 2016 2
97 27608006 Roles of Voltage-Gated Tetrodotoxin-Sensitive Sodium Channels NaV1.3 and NaV1.7 in Diabetes and Painful Diabetic Neuropathy. Int J Mol Sci 2016 Sep 5 1
98 27821467 A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels. Mol Pain 2016 4
99 27994738 Sulfonamides as Selective Na<sub>V</sub>1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement. ACS Med Chem Lett 2016 Dec 8 3
100 27998617 Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Can J Cardiol 2017 Feb 3