51 | 23760503 | Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin huwentoxin-IV (μ-TRTX-Hh2a). | J Biol Chem | 2013 Aug 2 |
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52 | 23818614 | Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels. | Proc Natl Acad Sci U S A | 2013 Jul 16 |
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53 | 23836888 | CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking. | J Biol Chem | 2013 Aug 23 |
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54 | 23874707 | Linkage between increased nociception and olfaction via a SCN9A haplotype. | PLoS One | 2013 |
1 |
55 | 23986482 | Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells. | J Cell Sci | 2013 Nov 1 |
2 |
56 | 24082113 | Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models. | Proc Natl Acad Sci U S A | 2013 Oct 22 |
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57 | 24154831 | Ion channel recordings on an injection-molded polymer chip. | Lab Chip | 2013 Dec 21 |
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58 | 24192167 | Structural and docking studies of potent ethionamide boosters. | Acta Crystallogr C | 2013 Nov |
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59 | 24272479 | Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough. | Lung | 2014 Feb |
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60 | 24401712 | Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H. | J Neurophysiol | 2014 Apr |
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61 | 24486399 | Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate. | Eur J Pharmacol | 2014 Mar 15 |
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62 | 24534904 | Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. | Anesthesiology | 2014 Jun |
2 |
63 | 24566628 | An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition. | Infect Immun | 2014 May |
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64 | 24840382 | Upregulation of nav1.7 through high salt loading: (mol pain 2013;9:39). | J Neurogastroenterol Motil | 2014 Apr 30 |
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65 | 24866741 | Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels. | Br J Pharmacol | 2014 Oct |
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66 | 25026046 | Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels. | J Med Chem | 2014 Aug 14 |
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67 | 25029427 | Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis. | J Clin Endocrinol Metab | 2014 Sep |
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68 | 25176194 | The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7. | Bioorg Med Chem Lett | 2014 Sep 15 |
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69 | 25218973 | Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels. | Peptides | 2015 Jun |
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70 | 25221944 | Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain. | PLoS One | 2014 |
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71 | 25240195 | Protein kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III-IV linker. | FEBS Lett | 2014 Nov 3 |
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72 | 25466191 | Dibenzazepines and dibenzoxazepines as sodium channel blockers. | Bioorg Med Chem Lett | 2015 Jan 1 |
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73 | 25658507 | Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel. | J Med Chem | 2015 Mar 12 |
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74 | 26068619 | Comparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine. | PLoS One | 2015 |
8 |
75 | 26187311 | Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs. | Eur J Pharmacol | 2015 Oct 5 |
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76 | 26220736 | Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. | Br J Pharmacol | 2015 Oct |
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77 | 26225903 | Activation of κ Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. | ACS Chem Neurosci | 2015 Oct 21 |
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78 | 26351759 | Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? | Pulm Pharmacol Ther | 2015 Dec |
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79 | 26429937 | Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7. | Mol Pharmacol | 2015 Dec |
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80 | 26581770 | The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. | Sci Rep | 2015 Nov 19 |
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81 | 26586647 | A review of the use of ethionamide and prothionamide in childhood tuberculosis. | Tuberculosis (Edinb) | 2016 Mar |
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82 | 26634308 | Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7. | Nat Commun | 2015 Dec 4 |
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83 | 26859646 | Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity. | Anesthesiology | 2016 May |
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84 | 26890998 | Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx-1. | J Med Chem | 2016 Mar 24 |
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85 | 26891306 | Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin. | Mar Drugs | 2016 Feb 16 |
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86 | 26991361 | Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening. | Assay Drug Dev Technol | 2016 Mar |
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87 | 27033404 | Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. | Fitoterapia | 2016 Jun |
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88 | 27050761 | Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. | PLoS One | 2016 |
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89 | 27088781 | Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. | JAMA Neurol | 2016 Jun 1 |
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90 | 27162340 | Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7. | Proc Natl Acad Sci U S A | 2016 May 24 |
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91 | 27215841 | Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels. | Elife | 2016 May 24 |
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92 | 27291053 | Historical Contingency in a Multigene Family Facilitates Adaptive Evolution of Toxin Resistance. | Curr Biol | 2016 Jun 20 |
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93 | 27363506 | Efficacy, safety, and tolerability of lacosamide in patients with gain-of-function Nav1.7 mutation-related small fiber neuropathy: study protocol of a randomized controlled trial-the LENSS study. | Trials | 2016 Jun 30 |
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94 | 27402262 | [Pain and analgesia : Mutations of voltage-gated sodium channels]. | Schmerz | 2017 Feb |
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95 | 27587537 | The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels. | Mol Pharmacol | 2016 Nov |
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96 | 27598514 | SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing. | PLoS One | 2016 |
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97 | 27608006 | Roles of Voltage-Gated Tetrodotoxin-Sensitive Sodium Channels NaV1.3 and NaV1.7 in Diabetes and Painful Diabetic Neuropathy. | Int J Mol Sci | 2016 Sep 5 |
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98 | 27821467 | A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels. | Mol Pain | 2016 |
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99 | 27994738 | Sulfonamides as Selective Na<sub>V</sub>1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement. | ACS Med Chem Lett | 2016 Dec 8 |
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100 | 27998617 | Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | Can J Cardiol | 2017 Feb |
3 |