Title : Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.

Pub. Date : 2014 Mar 15

PMID : 24486399






2 Functional Relationships(s)
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Protein Name
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1 BAB enhanced the onset of slow inactivation of Nav1.7 and Nav1.8 currents but not of Nav1.6 currents. butamben sodium voltage-gated channel alpha subunit 9 Homo sapiens
2 At clinically relevant concentrations (1-100muM), BAB is thus a more potent inhibitor of peripheral TTX-sensitive TTXs, Nav1.7 and TTX-resistant NaV1.8 Na(+) channels than of motor neuron axonal Nav1.6 Na(+) channels. butamben sodium voltage-gated channel alpha subunit 9 Homo sapiens