phosphatase and tensin homolog ; Rattus norvegicus






351 Article(s)
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1 11146227 Absence of PTEN/MMAC1 gene mutations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats. Cancer Lett 2001 Jan 26 6
2 11448956 The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival. J Biol Chem 2001 Sep 21 1
3 11784722 PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. J Biol Chem 2002 Mar 29 1
4 12414116 Enhanced phosphorylation of PTEN in rat brain after transient middle cerebral artery occlusion. Brain Res 2002 Nov 8 2
5 12461751 Recurrent allelic imbalance at the rat Pten locus in DMBA-induced fibrosarcomas. Genes Chromosomes Cancer 2003 Jan 2
6 12700235 Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase. J Biol Chem 2003 Jul 18 4
7 12939597 Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver. Hepatology 2003 Sep 5
8 14634032 Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats. J Pharmacol Exp Ther 2004 Mar 3
9 14700555 Multiple signaling pathways are involved in the regulation of IGF-I receptor inhibition of PTEN-enhanced apoptosis. Growth Horm IGF Res 2004 Feb 1
10 14713550 Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liver. Toxicol Pathol 2004 Jan-Feb 3
11 15231710 Control of phosphatase and tensin homolog (PTEN) gene expression in normal and neoplastic thyroid cells. Endocrinology 2004 Oct 3
12 15482376 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats. Fundam Clin Pharmacol 2004 Oct 4
13 15523589 Increase of PTEN gene expression in insulin resistance. Horm Metab Res 2004 Oct 1
14 15569824 Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia. Arterioscler Thromb Vasc Biol 2005 Feb 2
15 15646324 [Effect of captopril on expression of PTEN in aorta of aortic-induced hypertensive rats]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2004 Dec 8
16 15893727 Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD. Mol Cell 2005 May 13 1
17 15905199 The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. Carcinogenesis 2005 Oct 2
18 15929827 [Expression of tumor suppressor PTEN in hypertrophy cardiomyocyte]. Zhonghua Xin Xue Guan Bing Za Zhi 2005 Mar 1
19 16188065 [PTEN negatively regulates isoproterenol-induced cardiac hypertrophy and effects of captopril on PTEN expression]. Zhonghua Xin Xue Guan Bing Za Zhi 2005 Aug 5
20 16284183 PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioning. Circ Res 2005 Dec 9 3
21 16331670 Association of the phosphatase and tensin homolog gene (PTEN) with smoking initiation and nicotine dependence. Am J Med Genet B Neuropsychiatr Genet 2006 Jan 5 6
22 16474401 Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nat Med 2006 Mar 1
23 16502258 PTEN: a crucial mediator of mitochondria-dependent apoptosis. Apoptosis 2006 Feb 1
24 16738317 Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo. Mol Cell Biol 2006 Jun 1
25 16757079 Dietary sphingolipids suppress a subset of preneoplastic rat liver lesions exhibiting high PTEN, low phospho-Akt and high levels of ceramide species. Food Chem Toxicol 2006 Sep 3
26 16762504 Down-regulation of PTEN by sodium orthovanadate inhibits ASK1 activation via PI3-K/Akt during cerebral ischemia in rat hippocampus. Neurosci Lett 2006 Aug 14 5
27 16802321 PTEN, Akt, and GSK3beta signalling in rat primary cortical neuronal cultures following tumor necrosis factor-alpha and trans-4-hydroxy-2-nonenal treatments. J Neurosci Res 2006 Aug 15 5
28 16898871 Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine. Nutr Cancer 2006 1
29 16973299 Ischemic preconditioning negatively regulates plenty of SH3s-mixed lineage kinase 3-Rac1 complex and c-Jun N-terminal kinase 3 signaling via activation of Akt. Neuroscience 2006 Dec 1 1
30 17218436 Abnormal glucose homeostasis in adult female rat offspring after intrauterine ethanol exposure. Am J Physiol Regul Integr Comp Physiol 2007 May 2
31 17302912 Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway. J Neurochem 2007 Jul 5
32 17823648 Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells. J Psychiatry Neurosci 2007 Sep 1
33 18036354 Atorvastatin inhibits GSK-3beta phosphorylation by cardiac hypertrophic stimuli. Biochim Biophys Acta 2008 Jan-Feb 6
34 18054565 Aging gastropathy-novel mechanisms: hypoxia, up-regulation of multifunctional phosphatase PTEN, and proapoptotic factors. Gastroenterology 2007 Dec 1
35 18095365 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis. Proteomics 2008 Jan 1
36 18166358 PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism. Gastroenterology 2008 Jan 1
37 18385463 Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspring. Am J Physiol Regul Integr Comp Physiol 2008 Jun 4
38 18571742 Tat-3L4F does not significantly affect spatial learning and memory. Behav Brain Res 2008 Nov 21 2
39 18772044 PTEN-5-HT2C coupling: a new target for treating drug addiction. Prog Brain Res 2008 4
40 18931933 Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A. Biogerontology 2009 Aug 1
41 19070673 Regulation of mTOR and p70 S6 kinase by the muscarinic M4 receptor in PC12 cells. Cell Biol Int 2009 Feb 1
42 19080402 [The changes of PTEN/Akt1 expression and cell proliferation in pulmonary arterial smooth muscle cells induced by hypoxia in rats]. Zhonghua Jie He He Hu Xi Za Zhi 2008 Aug 1
43 19266280 S-nitrosylation of PTEN Invovled in ischemic brain injury in rat hippocampal CA1 region. Neurochem Res 2009 Aug 3
44 19469643 Genistein mechanisms and timing of prostate cancer chemoprevention in lobund-wistar rats. Asian Pac J Cancer Prev 2009 Jan-Mar 2
45 19553907 The protective effect of early hypothermia on PTEN phosphorylation correlates with free radical inhibition in rat stroke. J Cereb Blood Flow Metab 2009 Sep 3
46 19623194 Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia. J Cereb Blood Flow Metab 2009 Dec 2
47 19633808 Propylthiouracil, independent of its antithyroid effect, promotes vascular smooth muscle cells differentiation via PTEN induction. Basic Res Cardiol 2010 Jan 7
48 19785956 [The effect of DHEA on AKT signal pathway on transplanted Morris hepatomas in rats]. Zhonghua Gan Zang Bing Za Zhi 2009 Sep 1
49 20050973 Neuroprotection by baicalein in ischemic brain injury involves PTEN/AKT pathway. J Neurochem 2010 Mar 1
50 20097771 Pharmacological inhibition of PTEN limits myocardial infarct size and improves left ventricular function postinfarction. Am J Physiol Heart Circ Physiol 2010 Apr 4