Title : PTEN: a crucial mediator of mitochondria-dependent apoptosis.

Pub. Date : 2006 Feb

PMID : 16502258






1 Functional Relationships(s)
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1 Of note, the STS-induced marked increase in the cellular ROS level, release of cytochrome c and activation of caspase 3 were inhibited in cultured hippocampal cells when PTEN was knocked down by a specific antisense. Reactive Oxygen Species phosphatase and tensin homolog Rattus norvegicus