OTU domain, ubiquitin aldehyde binding 1 ; Mus musculus






15 Article(s)
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1 28083634 Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo. Acta Neuropathol 2017 May 1
2 30282802 OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination. J Biol Chem 2018 Nov 23 1
3 31824482 T Regulatory Cells From Non-obese Diabetic Mice Show Low Responsiveness to IL-2 Stimulation and Exhibit Differential Expression of Anergy-Related and Ubiquitination Factors. Front Immunol 2019 1
4 32005664 Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease. J Biol Chem 2020 Mar 13 3
5 32024978 The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Cell Mol Immunol 2021 Jun 1
6 32049508 Comparison of Cross-Regulation by Different OTUB1:E2 Complexes. Biochemistry 2020 Mar 3 2
7 32842143 Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma. Blood 2021 Mar 18 1
8 32999280 Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf. Cell Death Dis 2020 Sep 30 6
9 33627137 Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis. Cell Commun Signal 2021 Feb 24 3
10 33712742 OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation. Cell Death Differ 2021 Jul 3
11 34591986 OTUB1 alleviates NASH through inhibition of the TRAF6-ASK1 signaling pathways. Hepatology 2022 May 2
12 35163456 The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism. Int J Mol Sci 2022 Jan 28 5
13 35490780 ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1. J Biol Chem 2022 Apr 28 1
14 35494004 Solasonine Inhibits Pancreatic Cancer Progression With Involvement of Ferroptosis Induction. Front Oncol 2022 1
15 35500217 S-Nitrosylation of OTUB1 Alters Its Stability and Ubc13 Binding. ACS Chem Neurosci 2022 May 18 2