Pub. Date : 2020 Mar 3
PMID : 32049508
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OTUB1 is a highly expressed cysteine protease that specifically cleaves K48-linked polyubiquitin chains. | Cysteine | OTU domain, ubiquitin aldehyde binding 1 | Mus musculus |
| 2 | OTUB1 can non-catalytically suppress the ubiquitin conjugating activity of its E2 partners by sequestering the charged E2~Ub thioester and preventing ubiquitin transfer. | Cy5-benzyl thioester | OTU domain, ubiquitin aldehyde binding 1 | Mus musculus |