nuclear receptor subfamily 1, group I, member 2 ; Mus musculus






324 Article(s)
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301 33387840 Lipidomic profiling reveals triacylglycerol accumulation in the liver during pregnane X receptor activation-induced hepatomegaly. J Pharm Biomed Anal 2021 Feb 20 5
302 33398415 The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice. Arch Toxicol 2021 Mar 2
303 33409597 Vitamin K in CKD Bone Disorders. Calcif Tissue Int 2021 Apr 3
304 33487623 Chronic low-dose exposure to imidacloprid potentiates high fat diet-mediated liver steatosis in C57BL/6J male mice. J Vet Med Sci 2021 Apr 3 1
305 33636438 Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics. Bioorg Chem 2021 Apr 5
306 33687065 Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2-mediated mechanism. Br J Pharmacol 2021 Jun 3
307 33777316 <i>Eurotium cristatum</i> Fermented Loose Dark Tea Ameliorates Cigarette Smoke-Induced Lung Injury by MAPK Pathway and Enhances Hepatic Metabolic Detoxification by <i>PXR</i>/<i>AhR</i> Pathway in Mice. Oxid Med Cell Longev 2021 1
308 33777700 Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis. Toxicol Rep 2021 5
309 33782543 PXR mediates mifepristone-induced hepatomegaly in mice. Acta Pharmacol Sin 2022 Jan 3
310 33879258 The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice. Microbiome 2021 Apr 20 1
311 33965855 Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR-Nrf2 pathway. Environ Pollut 2021 Sep 15 6
312 33986260 Prevention of D-GalN/LPS-induced ALI by 18β-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation. Cell Death Dis 2021 May 13 9
313 34303773 Di(2-ethylhexyl)phthalate exposure exacerbates metabolic disorders in diet-induced obese mice. Food Chem Toxicol 2021 Oct 1
314 34415766 Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid-FXR-SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice. J Agric Food Chem 2021 Sep 1 7
315 34644426 St. John's Wort alleviates dextran sodium sulfate-induced colitis through pregnane X receptor-dependent NFκB antagonism. FASEB J 2021 Nov 6
316 34847399 Corrigendum to "Pregnane X receptor (PXR) protects against cisplatin-induced acute kidney injury in mice" [Biochim. Biophys. Acta, Mol. Basis Dis. 1867(3) 2021 Mar 1, 165996./BBADIS-20-505]. Biochim Biophys Acta Mol Basis Dis 2022 Feb 1 2
317 34851150 Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mice. Environ Health Perspect 2021 Dec 11
318 34861291 The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice. Toxicology 2022 Jan 15 2
319 35074011 Gut microbiota-derived metabolite 3-idoleacetic acid together with LPS induces IL-35<sup>+</sup> B cell generation. Microbiome 2022 Jan 24 2
320 35137921 Resveratrol ameliorates nutritional steatohepatitis through the mmu‑miR‑599/PXR pathway. Int J Mol Med 2022 Apr 2
321 35256948 Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice. Acta Pharm Sin B 2022 Feb 4
322 35401224 <i>Salvia miltiorrhiza</i> Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling. Front Pharmacol 2022 3
323 35406689 Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice. Cells 2022 Mar 26 2
324 35609418 Mice blocking Ser347 phosphorylation of pregnane x receptor develop hepatic fasting-induced steatosis and hypertriglyceridemia. Biochem Biophys Res Commun 2022 Jul 30 2