Title : Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling.

Pub. Date : 2022

PMID : 35401224






3 Functional Relationships(s)
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1 Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-kappaB Signaling. tanshinone nuclear receptor subfamily 1, group I, member 2 Mus musculus
2 Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-kappaB Signaling. Cisplatin nuclear receptor subfamily 1, group I, member 2 Mus musculus
3 Objective: The present study aims to provide evidence on the potential protective role of Salvia miltiorrhiza Bunge (Danshen) and its bioactive compound Tanshinone IIA (TanIIA) in AKI and to reveal the specific regulatory function of PXR/NF-kappaB signaling in AKI-induced renal inflammation. tanshinone nuclear receptor subfamily 1, group I, member 2 Mus musculus