autophagy related 12 ; Homo sapiens






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1 9852036 A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. J Biol Chem 1998 Dec 18 3
2 11096062 The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J Biol Chem 2001 Jan 19 4
3 12890687 The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification. J Biol Chem 2003 Oct 10 5
4 15155809 Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol Biol Cell 2004 Aug 1
5 16963840 Stimulation of ATG12-ATG5 conjugation by ribonucleic acid. Autophagy 2007 Jan-Feb 3
6 17404493 The inositol trisphosphate receptor in the control of autophagy. Autophagy 2007 Jul-Aug 1
7 17457038 Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12. Autophagy 2007 Jul-Aug 3
8 17986448 The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 2007 Dec 28 3
9 18670194 Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals. Autophagy 2008 Aug 1
10 19074260 Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes. Proc Natl Acad Sci U S A 2008 Dec 30 4
11 19197948 Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 2009 Apr 1
12 19417210 Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood 2009 Jul 2 1
13 20543569 Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells. Autophagy 2010 Aug 1
14 20629079 Dasatinib induces autophagic cell death in human ovarian cancer. Cancer 2010 Nov 1 1
15 20723759 ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 2010 Aug 20 2
16 20946021 Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells. J Med Food 2010 Dec 1
17 21595977 β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis. BMC Cancer 2011 May 20 1
18 21629657 Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PLoS One 2011 1
19 22024756 A PCR analysis of the ubiquitin-like conjugation systems in macroautophagy. Autophagy 2011 Dec 1
20 22152474 The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis. Mol Cell 2011 Dec 9 1
21 22170153 Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan. Autophagy 2012 Jan 1
22 22286278 High-throughput screening for anti-influenza A virus drugs and study of the mechanism of procyanidin on influenza A virus-induced autophagy. J Biomol Screen 2012 Jun 2
23 22342342 A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate. Mol Cell 2012 Mar 9 2
24 22617511 A tethering coherent protein in autophagosome maturation. Autophagy 2012 Jun 1
25 22784363 NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death. BMC Complement Altern Med 2012 Jul 11 2
26 23088497 Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 β-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibition. J Mol Signal 2012 Oct 22 1
27 23307622 Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment. Oncotarget 2012 Dec 3
28 23380587 Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Autophagy 2013 Apr 2
29 23494480 Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells. Apoptosis 2013 May 2
30 23500541 Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy. Biochem Pharmacol 2013 May 15 1
31 23591552 Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells. Int J Oncol 2013 Jun 1
32 23723573 Amikacin-induced Fin Reduction is Mediated by Autophagy. J Toxicol Pathol 2013 Mar 1
33 23769318 Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer. Lung Cancer 2013 Sep 1
34 24008736 WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma. Cell Death Dis 2013 Sep 5 1
35 24070470 Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy. Essays Biochem 2013 2
36 24485455 Molecular mechanism of autophagic membrane-scaffold assembly and disassembly. Cell 2014 Jan 30 1
37 24563301 Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells. Biotechnol Lett 2014 Jun 1
38 24817946 Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma. Int J Clin Exp Pathol 2014 1
39 24905352 Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. Autophagy 2014 Jul 1
40 24963637 Scaffolding the expansion of autophagosomes. Autophagy 2014 Jul 4
41 25259530 Trehalose improves human fibroblast deficits in a new CHIP-mutation related ataxia. PLoS One 2014 1
42 25537862 Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of AMP-activated protein kinase. Mol Cells 2015 1
43 25629784 WIPI2B links PtdIns3P to LC3 lipidation through binding ATG16L1. Autophagy 2015 1
44 25779081 On the mechanism underlying ethanol-induced mitochondrial dynamic disruption and autophagy response. Biochim Biophys Acta 2015 Jul 1
45 25891311 Silibinin, a natural flavonoid, induces autophagy via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3 in human MCF7 breast cancer cells. Oncol Rep 2015 Jun 1
46 26416454 MiR-200b regulates autophagy associated with chemoresistance in human lung adenocarcinoma. Oncotarget 2015 Oct 20 7
47 26558631 Rotenone Induces the Formation of 4-Hydroxynonenal Aggresomes. Role of ROS-Mediated Tubulin Hyperacetylation and Autophagic Flux Disruption. Mol Neurobiol 2016 Nov 1
48 26884967 Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways. Int J Clin Exp Med 2015 2
49 26987063 Goniothalamin induces apoptosis associated with autophagy activation through MAPK signaling in SK-BR-3 cells. Oncol Rep 2016 May 1
50 27200496 Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling. Environ Toxicol 2017 Mar 1