Title : The inositol trisphosphate receptor in the control of autophagy.

Pub. Date : 2007 Jul-Aug

PMID : 17404493






1 Functional Relationships(s)
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1 The IP(3)R antagonist xestospongin B induces autophagy in human cells through a pathway that requires the obligate contribution of Beclin-1, Atg5, Atg10, Atg12 and hVps34, yet is inhibited by ER-targeted Bcl-2 or Bcl-XL, two proteins that physically interact with IP(3)R. xestospongin B autophagy related 12 Homo sapiens